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Taiwanese company United Biomedical Inc. (UBI) Asia on Wednesday applied for emergency use authorization #EUA in Taiwan for its #COVID19 vaccine candidate, after releasing the interim results of its Phase 2 clinical trials last weekend.
https://focustaiwan.tw/sci-tech/202106300021
聯亞疫苗擠身全球10個受關注的高潛能二代疫苗選手！
4月29日，Clinical Trials Arena （臨床試驗論壇——一個為高階專業人士提供全球臨床試驗市場相關新聞、觀點和趨勢的平台）發表一篇名為「10個下一代新冠肺炎疫苗選手 」（10 next-gen Covid-19 vaccines in the race for approval）的分析，聯亞研發中的疫苗，擠身受關注的這十大高潛能疫苗之一！
二代疫苗因為第一代疫苗的副作用連連，而備受期待！
報告內容中說：
與武漢肺炎的戰爭仍然在持續中，雖然目前一線藥廠已紛紛推出有效疫苗，但無論AZ、嬌生、BNT，在世界各地都有傳出副作用，例如血栓或是心肌炎等。世界因此轉向注意那些研發速度較慢，但製作方法比較不一樣的疫苗。
本文列出10個WHO登記有案的疫苗，已進入最後階段的高潛能疫苗供參。
～～～
Vaxxinity (聯亞)
Candidate name: UB-612
這支疫苗能同時活化Ｔ細胞跟Ｂ細胞，強化全面免疫能力。在台灣進行的實驗收取第一期60人，第二期3850人。
一期研究表明 UB-612 的安全性、耐受性和免疫原性的評估結果，發現該疫苗通常具有良好的耐受性，並引發了強烈的疫苗誘導的 CD4+/CD8+ T 細胞抗體反應。
Vaxxinity 也已和醫療公司 Dasa 合作在巴西進行 II/III 期試驗，並與內布拉斯加大學合作在美國進行 I/II 期試驗。
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以上是內容摘要。
全世界還有一百多個疫苗在研發，能夠被關注，視為十個臨床試驗中的高潛能選手之一，表示是一個值得期待的二代疫苗。雖然結果還在未定之天，但是至少我們不必妄自菲薄！
台灣的反對黨在國產疫苗的政策鬥爭中，詆毀國產疫苗的公信力，和國際產業科學形容國產疫苗的高潛能，形成了諷刺的對比！
台灣需要發展疫苗產業，不只如此，醫藥生技產業急起直追，從中國鎖藥危機中，取回我們的「醫藥主權」、「疫苗主權」，已經是國安戰略的問題。
根據「今周刊」的報導，除了
B N T疫苗，中資取得台灣授權的藥物，包括抗生素、癌症用藥等，高達130種之多。這問題呈現的非常清楚，中國正利用商業手段，促成「醫統」，企圖用鎖藥、鎖疫苗， 逼我們就範、引我們內亂；這次讓我們買不到BNT疫苗，赤裸裸的演習了一次，政府被逼得束手無策，最後美、日出手相助，過程的紛亂，餘悸猶存！
今天提供這個資料，是希望大家拉出一個全球比較的視野，平等的看待國產疫苗。
Mechanism: Multitope peptide-based vaccine
Trial phase: Phase II/III
Vaxxinity (formerly COVAXX), a subsidiary of United Biomedical (UBI), is developing UB-612, a multitope protein/synthetic peptide-based vaccine candidate for Covid-19. UB-612 is designed to activate both T-cell and B-cell immunity in the body and has shown neutralising antibody activity in mice, rats, and guinea pigs.
In Taiwan, a Phase I trial of up to 60 participants is underway, and a Phase II trial of 3,850 participants has been initiated.
Results from the Phase I study, which evaluated the safety, tolerability, and immunogenicity of UB-612, showed that the vaccine was generally well-tolerated and elicited robust vaccine-induced CD4+/CD8+ T cell antibody responses.
Vaxxinity is also partnering with medical company Dasa for a Phase II/III trial in Brazil, and with the University of Nebraska for Phase I/II trials in the United States.
https://www.clinicaltrialsarena.com/analysis/10-next-gen-covid-19-vaccines-in-the-race-for-approval/?fbclid=IwAR1EMGP5RBoJ0oX_KCMhgAVLG-hV2sVQDN4SAaGK80beBqAjJR_mX-4RxBU
Foxsemicon Integrated Technology Inc., a subsidiary of Apple supplier Foxconn Group, reported a #COVID19 cluster among its employees late Monday, making it the fourth electronics company in northern Miaoli County to be hit by the disease.
https://focustaiwan.tw/business/202106080007
PlayerUnknown's Battlegrounds (PUBG) is an online multiplayer battle royale game developed and published by PUBG Corporation, a subsidiary of South Korean video game company Bluehole. The game is based on previous mods that were created by Brendan "PlayerUnknown" Greene for other games using the film Battle Royale for inspiration, and expanded into a standalone game under Greene's creative direction. In the game, up to one hundred players parachute onto an island and scavenge for weapons and equipment to kill others while avoiding getting killed themselves. The available safe area of the game's map decreases in size over time, directing surviving players into tighter areas to force encounters. The last player or team standing wins the round
PlayerUnknown's Battlegrounds (PUBG) is an online multiplayer battle royale game developed and published by PUBG Corporation, a subsidiary of South Korean video game company Bluehole. The game is based on previous mods that were created by Brendan "PlayerUnknown" Greene for other games using the film Battle Royale for inspiration, and expanded into a standalone game under Greene's creative direction. In the game, up to one hundred players parachute onto an island and scavenge for weapons and equipment to kill others while avoiding getting killed themselves. The available safe area of the game's map decreases in size over time, directing surviving players into tighter areas to force encounters. The last player or team standing wins the round
PlayerUnknown's Battlegrounds (PUBG) is an online multiplayer battle royale game developed and published by PUBG Corporation, a subsidiary of South Korean video game company Bluehole. The game is based on previous mods that were created by Brendan "PlayerUnknown" Greene for other games using the film Battle Royale for inspiration, and expanded into a standalone game under Greene's creative direction. In the game, up to one hundred players parachute onto an island and scavenge for weapons and equipment to kill others while avoiding getting killed themselves. The available safe area of the game's map decreases in size over time, directing surviving players into tighter areas to force encounters. The last player or team standing wins the round
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