《糖尿病救星》書中的理論，第二型糖尿病是因為脂肪堆積在胰臟的胰島細胞，變成脂肪胰 (fatty pancreas)，讓胰島素分泌功能變差，血糖才高起來。
一篇分析 97 位女性的研究，包含有妊娠糖尿病史、血糖偏高 (包含空腹血糖偏高、葡萄糖耐受異常、第二型糖尿病)、正常血糖等不同類型，用核磁共振測量胰臟脂肪和 ß 細胞分泌胰島素的功能。
結果測量的胰臟脂肪，跟 BMI、腰圍、肝臟脂肪、內臟脂肪有正相關，跟 ß 細胞分泌胰島素能力沒有關聯。
不是只有一篇文獻說沒有相關，書中寫的斬釘截鐵，但事實上這個理論還有爭議。
https://www.ncbi.nlm.nih.gov/pubmed/?term=29947782
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我不是指脂肪胰導致糖尿病的理論完全錯，只是還有爭議。正方和反方的文獻都有，下列是反方的:
"No relationship was found between pancreatic adipose tissue infiltration and beta cell function, regardless of glucose tolerance status."
https://www.ncbi.nlm.nih.gov/pubmed/25740696
"Pancreatic fat content was increased in individuals with IFG and/or IGT, without a direct relation with β-cell function."
https://www.ncbi.nlm.nih.gov/pubmed/21084401
"Fatty pancreas was not associated with HOMA-β after adjusting for liver fat and body mass index."
https://www.ncbi.nlm.nih.gov/pubmed?term=24492753
"The presence of pancreatic fat is not related to prediabetes or diabetes, which suggests that it has little clinical relevance for an individual's glycemic status."
https://www.ncbi.nlm.nih.gov/pubmed/25658037
"After adjusting for age, gender and BMI the association was attenuated."
https://www.ncbi.nlm.nih.gov/pubmed/28520813
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