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山中伸彌(日语:山中伸弥/やまなかしんや Yamanaka Shin'ya ,1962年9月4日-),日本幹細胞科學家,現任京都大学教授、UCSF附屬格拉德斯通心血管病研究所( ...
#2. 《Nature》子刊:長期山中因子治療安全逆轉小鼠衰老
近(7)日,美國沙克研究所(Salk Institute)測試俗稱「山中因子」(Yamanaka factors)的Oct4、Sox2、Klf4和cMyc四種轉錄因子,在小鼠身上抗衰老的效果。
山中伸彌團隊發現,以病毒把4個基因(Yamanaka factors;直譯「山中因子」)帶進成年小鼠的皮膚細胞中,可以使已分化的細胞轉化成具有胚胎幹細胞特性的細胞。
蛋白药物开发:转录因子药物开发平台 ... 转录因子是可直接调控基因达到影响生理表现的大分子蛋白质。 2012年诺贝尔奖得主中山伸弥所发现的”Yamanaka Factors”是近来最有名的 ...
#5. 诱导多能性 - JoVE
这些因素也被称为是Yamanaka 因素后研究者们发现他们重编程的影响。 多个方法可用于诱导这些转录因子的表达。最常见和最有效的方法是病毒的使用改性能够转录因子基因 ...
#6. 矽谷生技公司Altos Labs募資30億美元研發抗老新藥
OSKM因子,也因此命名為「山中因子」(Yamanaka Factors)。後續的科學家Juan Carlos Izpisua Belmonte提出的研究發現,山中因子植入小鼠的皮膚纖維母 ...
#7. 再生醫學: - 個人網頁空間
學會對於幹細胞研究及臨床轉譯指南的中文譯本,加入在附錄中,期以提供國內探討 ... 又稱為山中因子Yamanaka factors)到,成功誘導纖維母細胞再程序化,進而形成類似胚.
#8. 再生醫學之細胞核重編程方法概論
defined factors. Cell 2006; 126: 663-76. 18. Yamanaka S. Induced pluripotent stem cells: past, present, and future. Cell Stem Cell 2012; 10: 678-84.
#9. 科学家新疗法让中年老鼠“重返青春” - Chinadaily.com.cn
Researchers are cautious about using Yamanaka factors in humans because previous work has shown that fully reprogrammed cells can turn into ...
#10. 創世紀季刊
finger Transcription factors ... carcinoma (EC) cells Transcription factors ... 莉羊”複製;1998年由Jame Thomson建立的人類幹細胞;2006年由Shinya Yamanaka 從 ...
#11. 建立安全的誘導性幹細胞的重新編寫方法__臺灣博碩士論文知識 ...
幹細胞分化成各種型態細胞的能力稱之為多能性,但終端分化的體細胞則失去了這些多能性。在近年的研究中發現,將體細胞大量表現特定的幹細胞轉錄因子(Yamanaka 因子, ...
#12. 使用带有Yamanaka因子的hLMP-3将小鼠胚胎成纤维细胞直接 ...
大型骨缺损和骨折后的骨丢失仍然是整形外科医生的重大挑战。我们的研究旨在找到一种可行的,适用的生物治疗方法来克服ESC / iPSC技术的局限性。我们将Yamanaka因子与 ...
#13. 上皮黏附因子與Oct4或Klf4可以透過活化轉錄激活蛋白3與低氧 ...
However, until now, most of the iPSCs are generated by the transduction of four Yamanaka factors. The epithelial cell adhesion molecule (EpCAM), ...
#14. YAMANAKA 中文是什么意思- 中文翻译 - Tr-ex
以下是许多翻译的例句,其中包含“YAMANAKA” - 英语-中文翻译和搜索引擎英语翻译。 ... In these animals the cyclic induction of the Yamanaka factors led to ...
#15. 引文資訊
... cellular reprogramming by ectopic expression of endogenous transcription factors (also, known as Yamanaka factors), such as Oct4, Sox2, ...
#16. 科技部補助專題研究計畫報告 - NCKU
中文 摘要:該項目通過增強全層傷口微環境中的細胞能力促進組織再生研究了 ... exogenous Yamanaka factors a differentiated cell will.
#17. Introduction to Somatic Cell (体细胞) | 学术写作例句词典
Induced pluripotent stem cells (iPSCs) originate from the reprogramming of adult somatic cell s using four Yamanaka transcription factors.
#18. 山中伸彌 - 中文百科
山中伸彌(日語:山中伸弥/やまなかしんや Yamanaka Shin'ya,1962年9月4日-) ... 關鍵的轉錄因子:現稱山中因子(Yamanaka factors)的Sox2、Oct4、KLF4和c-Myc。
#19. 山中伸弥_百度百科
中文 名: 山中伸弥 ; 外文名: 英文:Shinya Yamanaka ; 国 籍: 日本 ; 民 族: 大和民族 ; 出生日期: 1962年9月4日 ...
#20. NCU Institutional Repository-博碩士論文982204010 詳細資訊
Recent studies have shown that somatic cells can be reprogrammed by over-expression of defined transcription factors (Yamanaka factors, ...
#21. STPI產業資訊服務電子報:第983 期(2022-04-15)
... 可以將皮膚細胞的生物時鐘倒退30年的技術,透過將四種被稱為「山中因子(Yamanaka factors)」的特殊細胞來逆轉細胞發育,從而將成人的皮...more.
#22. Kim Forest 金萬林- Yamanaka會得諾貝爾獎不令人意外,發現他 ...
Yamanaka 會得諾貝爾獎不令人意外,發現他還是UCSF的PI,果真UCSF出高人, ... 對人類醫學的貢獻極大,所以這四個基因已被命名成Yamanaka factors,當然有愈來愈多的看法 ...
#23. iThenticate - F6Publishing
小提示: 只搜索中文(简体)结果,可在学术搜索设置指定搜索语言 ... Yamanaka factors were chosen for pluripotent cell generation (7), they are generally are ...
#24. 期刊界All Journals 搜尽天下杂志传播学术成果专业期刊搜索 ...
2. Induction of pluripotency by defined factors · Keisuke Okita Shinya Yamanaka 《Experimental cell research》2010,316(16):2565-441. 相似文献.
#25. 从蹩脚外科医生到细胞炼金术师 - azalea says
... 今年诺贝尔生理学或医学奖得主之一的山中伸弥(Shinya Yamanaka)的诺 ... Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors.
#26. 用脑膜细胞生成诱导的多能性干细胞的方法及其用途
[0008] 2006年,日本京都大学Yamanaka研究小组采用体外基因转染技术,从24个因子中 ... of pluripotent stem cells from adult humanfibroblasts by defined factors.
#27. Studies of Pluripotency in Embryonic Stem Cells and Induced ...
The results in this thesis confirm that somatic cells can be fully reprogrammed with the four Yamanaka factors. In addition, we have found that the ...
#28. 诱导多功能干细胞的研究进展
In 2006, Yamanaka found that four factors (Oct3/4, Sox2, Klf4, c-Myc) could induce mouse embryonic fibroblasts into an embryonic stem cell-like state, ...
#29. Brief Introduction of Rejuvenation Technology - 知乎专栏
本文中文版: 返老还童技术简述Brief Introduction of Rejuvenation ... In other words, through four Yamanaka factors, we can make cells ...
#30. Induced pluripotent stem cells - faCellitate
... by the introduction of four specific genes coding for transcription factors (MyC, Oct3/4, Sox2 and Klf4) (Tahahashi and Yamanaka, 2006).
#31. 幹細胞--未來:iPS細胞簡介(Stem cells - the future - VoiceTube
Shinya Yamanaka was able to ascertain the 24 most likely candidates. It took years of work. The next step was to narrow down factors,.
#32. Induced Pluripotent Stem Cell Research at Johns Hopkins
Gurdon of the University of Cambridge in England and Shinya Yamanaka of Kyoto University in Japan for discovering how to turn adult cells back into stem cells.
#33. cancerous tissue中文- 头条搜索 - 今日头条
Yamanaka factors – can rewind adult cells into youthful stem cells that are capable of forming almost any tissue... 可可英语. 3月10日.
#34. 香港中文大學學術研究文庫- Converis标准配置
... Mouse Oct4 Genes Using Engineered TALE and Cas9 Transcription Factors for Reprogramming ... 詳細描述organized by Deepak Srivastava and Shinya Yamanaka,.
#35. Human iPSC Models - Neurobiology of Alzheimers Disease
The iPSC technology was pioneered by Shinya Yamanaka, M.D., Ph.D., ... of four specific genes encoding transcription factors could convert adult cells into ...
#36. Mesenchymal and induced pluripotent stem cells
Takahashi and Yamanaka developed this technique where four transcription factors, OCT4, SOX2, KLF4, and C-MYC (shown by the acronym OSKM), were ...
#37. Shutting down EpCAM kills tumor cells and prevents their ...
... Shinya Yamanaka, succeeded in reprogramming fibroblasts into pluripotent stem cells (iPSCs) using the four Yamanaka factors (OCT-4, ...
#38. 人工誘導多能性幹細胞平台開發之研究__國立陽明大學博碩士 ...
語文別: 中文. 論文頁數: 51. 中文關鍵詞: 誘導性多能幹細胞、細胞自噬、致腫瘤性. 外文關鍵詞: induced pluripotent stem cells、iPSCs、autophagy、tumorigenicity.
#39. 李劲松 - 中国科学院分子细胞科学卓越创新中心
... Kang J & Pei G. More synergetic cooperation of Yamanaka factors in ... (中文综述); Han Z, Chen D, Li J, Sun Q, Wang P, Huang Y & Du J.
#40. Transcriptome analysis of cells of different cycling speed during ...
Reprogramming somatic cells to induced pluripotency by Yamanaka factors is ... 中文描述. 通过Yamanaka因子将体细胞重编程为诱导多能性通常是缓慢和低效的,并且 ...
#41. 哈佛科學家:「衰老是種病」,而且能治療 - 天下雜誌
BBC News 中文 · BBC News 中文 ... 但是,我們發現3個叫做山中因子(Yamanaka factors)的基因可以安全逆轉衰老,而又不讓細胞失去其身份。
#42. Autologous Induced Stem-Cell–Derived Retinal Cells for ...
Chinese Translation 中文翻译. Article; Figures/Media. Metrics. 31 References; 757 Citing Articles; Letters; Related Articles ...
#43. 新技術能讓皮膚年輕30歲 - 壹讀
They then removed the Yamanaka factors and left the cells to grow. ... 註:中文文本為機器翻譯僅供參考,並非一一對應. 含注釋全文:.
#44. Shift Bioscience | 领英
Control of biological age with Yamanaka factors promises an effective solution to chronic disease, but risks teratoma formation. Shift Bioscience is focused ...
#45. Youthful Looks: Old Skin Cells Rejuvenated To Look Younger
The whole process of stem cell remodeling using four main molecules called Yamanaka factors takes about 50 days. A new method called 'mature ...
#46. pluripotent stem cells-翻译为中文-例句英语
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. 通过确定因素从小鼠胚胎细胞和成纤维细胞诱导多能干细胞.
#47. 多能干细胞:入门介绍 - Abcam中文官网
Takahashi K, Yamanaka S. (2006).Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors.
#48. In vivo Reprogramming of Adult Somatic Cells to Pluripotency by ...
Takahashi, K., et al. Induction Of Pluripotent Stem Cells From Adult Human Fibroblasts By Defined Factors. Cell. 131, 861-872 (2007). Takahashi, K., Yamanaka, ...
#49. 糖尿病藥物與糞便微生物移植可以抗老化嗎? - 科學月刊
... factor)——山中因子(Yamanaka factors)中13天,得以刪除細胞上與年齡有關的表觀遺傳因子,但保留該細胞作為皮膚細胞的功能。
#50. Signaling pathways regulating pluripotency of stem cells
... reprogramming somatic cells back to pluripotent state with defined reprogramming factors, Oct4, Sox2, Klf4 and c-Myc (also known as Yamanaka factors).
#51. 簡介誘導性全能幹細胞(iPSC)的發展與應用 - SLEKMED
... K., & Yamanaka, S. (2007). Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell, 131(5), 861–872.
#52. 兔抗小鼠IgG抗体,FITC偶联
兔抗小鼠IgG抗体,FITC偶联Chemicon®, from rabbit; find Sigma-Aldrich-AP160F MSDS, related peer-reviewed papers, technical documents, similar products & more ...
#53. Induced pluripotent stem cells, a giant leap for mankind ...
Although Yamanaka factors are commonly used for repro-gramming iPSC, other transcription factors, epigenetic regulators, microRNAs and/or small ...
#54. 从骨科医生到诺贝尔奖-山中伸弥的研究历程 - 科学网—博客
引言 山中伸弥(Shinya Yamanaka)获得诺奖已经有几天了, ... stem cells from mouse embryonic and adult fibroblast cultures by defined factors.
#55. Exhibition on Nobel Prize winner Dr Yamanaka - 大阪市立大学
Dr. Yamanaka entered the Osaka City University Graduate School of ... of platelet activating factors, a field closely related to mine.
#56. 诱导性多潜能干细胞(iPS)研究:现状与展望 - Engineering
2006年,日本Yamanaka研究小组通过将逆转录病毒介导的Oct - 4, Sox2, Klf4及c - Myc ... from mouse embryonic and adult fibroblast culture by defined factors [J ].
#57. 細胞骨架及微環境在間葉幹細胞分化的角色
中文 摘要間質幹細胞(Mesenchymal stem cell)為成體幹細胞的一種,主要存在於骨髓、週邊血臍帶、胎盤、或者脂肪組織中。間質幹細胞為一種具多功能性之幹細胞, ...
#58. Yamanaka Factors for the Cardio-Oncologist - Dr. Baliga's 'Got ...
00:14:25 - Yamanaka Factors for the Cardio-Oncologist Dr RR Baliga's 'Got Knowledge Doc' Podkasts for Physicians Takahashi K, Yamanaka S. Induction of ...
#59. CytoTune™-iPS 2.0 Sendai Reprogramming Kit - Thermo Fisher
This system continues to be easy to use and works with many different somatic cell types, using Sendai particles to deliver Yamanaka factors, ...
#60. 杜盛-中国科学院大学-UCAS
Tatsumi C, Taniguchi T, Du S, Chen QW, Yamanaka N, Otsuki K, Tateno R (2022). ... Understanding the limiting climatic factors on the suitable habitat of ...
#61. Masato Nakagawa | Interviste ai ricercatori | Nikon Europe B.V.
Professor Yamanaka discovered that four genes—Oct3/4, Sox2, Klf4, and c-Myc—can be used as factors to induce reprogramming. Reproducibility through methods ...
#62. A menagerie of stem-cell models - Document - Gale
Another option is to clone the species' own genes to make the Yamanaka factors, says stem-cell researcher Aleksei Menzorov at the Russian Academy of Sciences in ...
#63. 中山醫學大學電子論文系統
論文名稱(中文), 利用基因與環境因子進行台灣族群心血管疾病及痛風的SNP分析 ... Hyperlipidemia and High-density lipoprotein in Taiwanese Based on Risk Factors.
#64. 如果老化是可以治療的疾病呢? - Digitimes
藉由類似Shinya Yamanaka(2012醫學諾貝爾獎得主)的誘發多能 ... 的手段,的確也可以引入4個編碼有轉錄因子(transcription factors)的基因,消除細胞 ...
#65. US 2014/0242695 A1 - Protein-Induced Pluripotent Cell Technology ...
Yamanaka and several other labs have since demonstrated reprogramming can be ... pluripotent stem cells with the Yamanaka's factors or the SON factors, ...
#66. 科學家也許真的找到了長生不老藥 - 新唐人電視台
這些蛋白質的組合被稱為「山中要素」(Yamanaka factors)。 成功應用的例子 很多科學家認為山中的發現將為器官移植手術帶來革命。日本科學家為一位80 ...
#67. 藥物基因體學(pharmacogenomics)於化學治療之發展與應用
Seishima M, Yamanaka S, Fujisawa T, et al. Reactivation of human herpesvirus (HHV) family ... Factors predisposing to seizures in seriously ill infected ...
#68. A Potential Cure for Endometriosis-Related Infertility
Before Yamanaka, stem cells could only be made from embryo cells. ... erase the DNA program of these cells via the Yamanaka factors, ...
#69. 淺談幹細胞 - 藥學雜誌電子報106期
5. Takahashi K, Yamanaka S: Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006 ...
#70. (12)发明专利
[0008] 2006 年,日本京都大学Yamanaka 研究小组采用体外基因转染技术, 从24 个因子 ... adultfibroblast cultures by defined factors. ... 7-10(中文))。
#71. Elixir of life? A $3 billion bet on reversing the process of ...
Yamanaka factors, discovered in 2006 by Yamanaka Shinya of Kyoto University, are four gene-regulating proteins which serve, in essence, to ...
#72. Human Practice - iGEM 2014
Bootstrap中文网致力于为广大国内开发者提供详尽的中文文档、代码实例等,助力开发者掌握并 ... It is a plasmid containing the four Yamanaka factors(Oct4, Sox2, ...
#73. How Can Stem Cells Help With Cancer Treatment? - 义翘神州
ESCs are isolated from embryos, while iPSCs are induced from somatic cells in culture by overexpressing Yamanaka factors: Oct3/4 (cat#: HG13137), ...
#74. 诱导多能性干细胞快速高效产生的新型无血清培养基以及使用其 ...
( iPS细胞 ) ( Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors.
#75. Ageing: Cellular rejuvenation restores vision in mice | Nature
David Sinclair and colleagues demonstrate that expressing three Yamanaka transcription factors (proteins that can turn genes on and off) ...
#76. 法學論著-博碩論文-胚胎保護與基本權衝突-兼論國家對 ... - 法源
中文 摘要:, 從上世紀後葉的人工生殖、胚胎植入前基因診斷,到本世紀方興未艾的胚胎 ... Emotional factors and the in vitro fertilization and embryo transfer ...
#77. Regenerative medicine and drug discovery through iPSCs
iPSCs are produced by introducing special factors into cells of the body, ... were originally developed by Professor Shinya Yamanaka who received the 2012 ...
#78. Professor Kim Dale - University of Dundee
Although Myc transcription factors are extensively studied in the context of ... the inclusion of cMyc as one of the Yamanaka factors has renewed research ...
#79. 實驗性腦部犬蛔蟲症進展成神經退化疾病之分子機轉
中文 摘要, 犬蛔蟲症是盛行於世界各地的人畜共通寄生蟲疾病,主要是由感染犬蛔蟲所引起。 ... expressions of neurodegeneration-associated factors (NDAFs) and ...
#80. 這家矽谷新創獲貝佐斯大力投資!返老還春技術是未來趨勢?
另外還有巴西生物醫學研究中心的Manuel Serrano 博士,他是全球前幾個利用山中因子(Yamanaka factors)將小鼠模型的細胞返回誘導型多潛能 ...
#81. VIEWPOINT DYNAMICS AND CREATIVE DESIGN Inferences ...
VIEWPOINT DYNAMICS AND CREATIVE DESIGN Inferences from Analytical Methods based on Explanation ; TAKAYUKI SHIOSE ; TAKASHI YAMANAKA.
#82. Anti-Aging Effects of Mesenchymal Stem Cell Therapy in 2022
With our current knowledge of stem cells, it may be possible to test interventions that significantly delay aging. Many environmental factors ...
#83. Kazuhiro Yamanaka's solo exhibition "Visible X Invisible" is ...
Little inc. is also involved in design of the exhibition space, while Y2 Lighting Design is responsible for its lighting effects. Kazuhiro Yamanaka is highly ...
#84. Details about Midway judo club - Internal Revenue Service
Organizations eligible to receive tax-deductible charitable contributions. Users may rely on this list in determining deductibility of their contributions.
#85. bb棋牌平台登录 - 红楼梦中文网
這項技能包孕在朽邁細胞中(zhong)表達()“山中因子”(Yamanaka factors)。另外俄方发布的(de)视频中还浮现了苏-30SM战斗(dou)机,進修這件事。姚晨下定刻意去学演出成 ...
#86. 人诱导多能干细胞的成瘤性发生机制及干预策略- PMC - NCBI
Yamanaka 等[5]后来的研究也发现,在经过基因改造的121只实验鼠中有20%发生了肿瘤 ... peripheral blood using BCL-XL together with Yamanaka factors[J] PLoS One.
#87. Pair of 'liver eating' killer whales scare off great white shark ...
7 天前 — ... 한국 (한국어), 中华人民共和国 (简体中文), 台灣 (繁體中文) ... Shinya Yamanaka.who showed that when four molecules (Yamanaka factors) are ...
#88. 山中伸彌
^ Kazutoshi Takahashi, Shinya Yamanaka. Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors. Cell. 2006-08 ...
#89. 山中伸弥四因子替代者行诱导多能干细胞重编程的研究进展
Research progress in the substitutes of Yamanaka four factors in reprogramming induced-pluripotent stem cell · Authors: · CorrespondingAuthor: · DOI: · Foundation: ...
#90. 挑战常规!原本认为在构建iPS细胞中至关重要的Oct4实际上并 ...
2019年11月12日讯/生物谷BIOON/---自从2006年日本科学家山中伸弥(Shinya Yamanaka,如今是日本京都大学iPS细胞研究与应用中心负责人)发现了一种将 ...
yamanaka factors中文 在 Kim Forest 金萬林- Yamanaka會得諾貝爾獎不令人意外,發現他 ... 的推薦與評價
Yamanaka 會得諾貝爾獎不令人意外,發現他還是UCSF的PI,果真UCSF出高人, ... 對人類醫學的貢獻極大,所以這四個基因已被命名成Yamanaka factors,當然有愈來愈多的看法 ... ... <看更多>