Here, we show that gp78, a membrane bound E3, binds to Insig-1 and is required for sterol-regulated ubiquitination of reductase. In addition, ... ... <看更多>
「gp78 uniprot」的推薦目錄：
gp78 uniprot 在 E3 ubiquitin-protein ligase AMFR - Homo sapiens (Human) 的相關結果
UniProt is the world's leading high-quality, comprehensive and freely accessible resource of protein sequence and functional information. ... <看更多>
gp78 uniprot 在 E3 ubiquitin-protein ligase AMFR - Mus musculus (Mouse) 的相關結果
The VCP/p97-AMFR/gp78 complex is involved in the sterol-accelerated ERAD degradation of HMGCR through binding to the HMGCR-INSIG1 complex at the ER membrane ( ... ... <看更多>
gp78 uniprot 在 associated degradation. | Literature citations | UniProt 的相關結果
Here we demonstrate that the ERAD E3 gp78 can ubiquitinate not only ERAD substrates, but also the machinery protein Ubl4A, a key component ... ... <看更多>
gp78 uniprot 在 GPR78 - G-protein coupled receptor 78 | UniProtKB - UniProt 的相關結果
Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, ... ... <看更多>
gp78 uniprot 在 AMFR - E3 ubiquitin-protein ligase AMFR | UniProtKB - UniProt 的相關結果
Component of a VCP/p97-AMFR/gp78 complex that participates in the final step of endoplasmic reticulum-associated degradation (ERAD) (PubMed:10456327, ... ... <看更多>
gp78 uniprot 在 Sterol-induced degradation of HMG CoA reductase ... - UniProt 的相關結果
Knockdown of either gp78 or Trc8 in SV-589 cells through RNA interference (RNAi) inhibited sterol-induced ubiquitination of reductase and ... ... <看更多>
gp78 uniprot 在 INSIG1 - Insulin-induced gene 1 protein - Cricetulus ... - UniProt 的相關結果
... SOAT2/ACAT2 when the lipid levels are low: initiates the ubiquitin-mediated degradation of SOAT2/ACAT2 via recruitment of the ubiquitin ligases AMFR/gp78. ... <看更多>
gp78 uniprot 在 2LVN: Structure of the gp78 CUE domain - RCSB PDB 的相關結果
The endoplasmic reticulum resident RING finger ubiquitin ligase (E3) gp78 regulates critical proteins via the ubiquitin-proteasome system to ... ... <看更多>
gp78 uniprot 在 The ubiquitin ligase gp78 promotes sarcoma metastasis by ... 的相關結果
由 YC Tsai 著作 · 2007 · 被引用 188 次 — Gp78 (also known as AMFR or RNF45) is a RING finger E3 ubiquitin ligase that is integral to the endoplasmic reticulum ... Go to all (7) records in UniProt ... ... <看更多>
gp78 uniprot 在 BMRB Entries for protein with UniProt ID: Q9UKV5 的相關結果
Entry ID Link Type Entity ID
18581 Sequence mapping 1
18582 Sequence mapping 2
18583 Sequence mapping 2 ... <看更多>
gp78 uniprot 在 Anti-Glycoprotein 78 Antibody, clone 3F3A | MABC949 的相關結果
E3 ubiquitin-protein ligase AMFR (UniProt Q9UKV5; also known as AMF receptor, Autocrine motility factor receptor, gp78, RING finger protein 45) is encoded by ... ... <看更多>
gp78 uniprot 在 Aggregated Views of Proteins - PDBe-KB Protein Pages 的相關結果
Uniprot : Q9UKV5go to UniProt. Biological function: E3 ubiquitin-protein ligase that ... Component of a VCP/p97-AMFR/gp78 complex that participates in the . ... <看更多>
gp78 uniprot 在 Q9UKV5 - Repository - SWISS-MODEL 的相關結果
Description Oligo‑state Range Ligands
Crystal Structure of the Ube2g2:RING‑G2BR complex Heteromer P60604 339‑393 2×ZN; 2...
Structure of the gp78 CUE domain monomer 453‑504
Solution structure of RUH‑076, a human CUE domain monomer 452‑502 ... <看更多>
gp78 uniprot 在 Protein Details for GP78 - null Caviid herpesvirus 2 - 21222 的相關結果
Identification and characterization of the guinea-pig cytomegalovirus glycoprotein H gene. Brady R.C., Schleiss M.R. et al. 1996, Uniprot. 19559454, Virology ... ... <看更多>
gp78 uniprot 在 RETREG1/FAM134B mediated autophagosomal ... - NCBI 的相關結果
Abbreviations: AMFR/GP78: autocrine motility factor receptor; ... MaxQuant and fragment peaks were searched against human UNIPROT database. ... <看更多>
gp78 uniprot 在 CORUM - Helmholtz Zentrum München 的相關結果
... Gene name synonyms, Organism, UniProt ID, Entrez-ID ... The gp78 complex facilitates ERAD, whereas the SVIP complex inhibits ERAD. ... <看更多>
gp78 uniprot 在 AMFR/gp78 Antibody (NBP2-15374) - Novus Biologicals 的相關結果
Cited in 2 publications. View Rabbit Polyclonal anti-AMFR/gp78 Antibody (NBP2-15374). Validated Applications: WB, Func, IHC, IHC-P, In vitro. ... <看更多>
gp78 uniprot 在 AMFR protein expression summary - The Human Protein Atlas 的相關結果
AMFR (gp78, RNF45) protein expression summary. ... Splice variant, UniProt, Protein class, Gene ontology, Length & mass, Signal peptide ... <看更多>
gp78 uniprot 在 AMFR (autocrine motility factor receptor) 的相關結果
Subsequently, gp78/AMFR was identified as the tumor autocrine motility factor receptor mediating tumor ... Gene ID, Transcript ID, Uniprot ... ... <看更多>
gp78 uniprot 在 Human Liver Cytochrome P450 3A4 Ubiquitination ... 的相關結果
Significance: This is the first mechanistic example of UBC7-gp78 ... b Residue numbers refer to UniProt sequences; accession numbers are as ... ... <看更多>
gp78 uniprot 在 AMFR Gene - GeneCards | AMFR Protein | AMFR Antibody 的相關結果
Component of a VCP/p97-AMFR/gp78 complex that participates in the final ... No data available for mRNA Expression by UniProt/SwissProt and ... ... <看更多>
gp78 uniprot 在 GP78 Antibody / AMFR (R32507) - NSJ Bioreagents 的相關結果
UniProt. Q9UKV5. Applications. Western blot : 0.5-1ug/ml. IHC (FFPE) : 1-2ug/ml. Flow cytometry : 1-3ug/million cells. Limitations. This GP78 antibody is ... ... <看更多>
gp78 uniprot 在 無題 的相關結果
"Membrane-associated ubiquitin ligase complex containing gp78 mediates ... accompanied by conservative changes to GO terms applied by UniProt.". ... <看更多>
gp78 uniprot 在 AMFR, autocrine motility factor receptor - Find My Gene 的相關結果
... finger protein 45, RING-type E3 ubiquitin transferase AMFR, GP78, RNF45,); NCBI Gene ID: 267; Species: Homo sapiens (Human); UNIPROT ID#>>A0A024R6R5 ... <看更多>
gp78 uniprot 在 Amfr MGI Mouse Gene Detail - autocrine motility factor receptor 的相關結果
gp78. Feature Type. protein coding gene. IDs. MGI:1345634. NCBI Gene: 23802. Alliance ... Protein Information. less. UniProt. 4 Sequences. Protein Ontology. ... <看更多>
gp78 uniprot 在 AMFR (autocrine motility factor receptor) | Gene Report - BioGPS 的相關結果
Q9UKV5 (UniProt) 603243 (OMIM) 888 (HomoloGene). Aliases: GP78, RNF45. Genome Location: chr16:56361452-56425545 (hg38). Function: Molecular Function. ... <看更多>
gp78 uniprot 在 603243 - AUTOCRINE MOTILITY FACTOR RECEPTOR; AMFR 的相關結果
GP78 · TEXT · ▽ Description · ▻ Cloning and Expression · ▻ Gene Function · ▻ Gene Structure · ▻ Mapping · ▻ REFERENCES. ... <看更多>
gp78 uniprot 在 KEGG T01001: 267 的相關結果
AMFR, GP78, RNF45. Name. (RefSeq) autocrine motility factor receptor ... LMBR1L-GP78-UBAC2 complex 267 (AMFR). BRITE hierarchy ... UniProt: Q9UKV5 ... ... <看更多>
gp78 uniprot 在 hydroxymethylglutaryl-CoA reductase (NADPH) and Organism ... 的相關結果
Search UniProt Accession: ... Insig are carriers for gp78, an E3 ubiquitin ligase that marks reductase for proteasomal degradation. ... <看更多>
gp78 uniprot 在 RETREG1/FAM134B mediated autophagosomal degradation ... 的相關結果
FAM134B mediated autophagosomal degradation of AMFR/GP78 and OPA1 —a dual ... RETREG1 antibody (UniProt ID: Q9H6L5) retrieved only. ... <看更多>
gp78 uniprot 在 ERLIN2 - Erlin-2 - Function 的相關結果
Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex (PubMed:21343306). Involved in regulation of ... ... <看更多>
gp78 uniprot 在 Gene Report: AT4G25230 - Phytozome 的相關結果
Location: Chr4:12923918..12929156 forward; Alias: RIN2; UniProt: ... (1 of 2) K10636 - autocrine motility factor receptor (AMFR, GP78). ... <看更多>
gp78 uniprot 在 AMFR - Wikipedia 的相關結果
Aliases · AMFR, GP78, RNF45, autocrine motility factor receptor. External IDs, OMIM: 603243 MGI: 1345634 HomoloGene: 888 GeneCards: AMFR ... ... <看更多>
gp78 uniprot 在 Gp78 E3 Ubiquitin Ligase: Essential Functions and ... - Frontiers 的相關結果
Glycoprotein 78 (Gp78) is an E3 ubiquitin ligase that prevents multifactorial deleterious accumulation of different misfolded proteins via ... ... <看更多>
gp78 uniprot 在 Genes search | AnalogYeast - Weizmann Institute of Science 的相關結果
Yeast Systematic Name Yeast Symbol SGDID Analog Name
YML101C CUE4 SGDID:S000004568 AMFR RNF45
YML101C CUE4 SGDID:S000004568 CUE1 KIS4 YMR264W YM815...
YML101C CUE4 SGDID:S000004568 AUP1 ... <看更多>
gp78 uniprot 在 ND1 domain - LMPID 的相關結果
Bait Uniprot Accession, P0C0A9. Bait Uniprot Identifier, SVIP_RAT ... ubiquitin-protein ligase Amfr (gp78) that mediates interaction with mouse Transitional ... ... <看更多>
gp78 uniprot 在 Erlin-2 (ERLIN2) - DSIMB 的相關結果
Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex (PubMed:21343306). Involved in regulation of ... ... <看更多>
gp78 uniprot 在 Gene O15503 | Protein INSIG1 - Overview - canSAR Black 的相關結果
... the ubiquitin ligases AMFR/gp78 and/or RNF139 (PubMed:12535518, PubMed:16168377, PubMed:22143767). ... uniprot · enzyme classification · PhosphoSitePlus. ... <看更多>
gp78 uniprot 在 Quality Control of ER Membrane Proteins by the RNF185 ... 的相關結果
acterized HRD1 and gp78 complexes (Christianson et al., 2011; ... MS/MS spectra were searched against the Uniprot human reference proteome database ... ... <看更多>
gp78 uniprot 在 AMFR Antibody#9590 - Cell Signaling Technology 的相關結果
Autocrine motility factor receptor (AMFR/gp78) is a putative seven transmembrane domain G protein-coupled receptor that functions, ... UniProt ID: Q9UKV5. ... <看更多>
gp78 uniprot 在 AMFR ELISA Kit (Autocrine Motility Factor Receptor) ELISA Kit 的相關結果
... E3 ubiquitin-protein ligase AMFR, gp78, Autocrine motility factor receptor, AMF receptor, RING finger protein 45, GP78, RNF45; UniProt: Q9UKV5 ... ... <看更多>
gp78 uniprot 在 H-InvDB - Locus view HIX0013050 的相關結果
Definition: E3 ubiquitin-protein ligase AMFR; EC=6.3.2.-; Autocrine motility factor receptor; AMF receptor; RING finger protein 45; gp78; ... ... <看更多>
gp78 uniprot 在 AMFR / E3 Ubiquitin-Protein Ligase AMFR Recombinant Protein 的相關結果
Component of the VCP/p97-AMFR/gp78 complex that enhances VCP/p97 binding to ... NCBI/Uniprot data below describe general gene information for AMFR. ... <看更多>
gp78 uniprot 在 UBE2G2 | bioCADDIE Data Discovery Index 的相關結果
Crystal structure of Ube2g2 complxed with the G2BR domain of gp78 at 1.8-A resolution PDB. ID: PDB:3H8K ... UB2G2_BOVIN UniProt:Swiss-Prot. ID: Q17QG5. ... <看更多>
gp78 uniprot 在 o94905 erln2_human - SwissPalm 的相關結果
Probably part of an AMFR/gp78 and INSIG1-containing ubiquitin ligase complex involved ... UniProt ID, Orthology source, Organism, Gene names, Protein name ... ... <看更多>
gp78 uniprot 在 Isotype：IgG Source：Rabbit Application：WB,IHC Storage ... 的相關結果
probably implicating an AMFR/gp78-containing ubiquitin ligase complex. Involved in regulation of cellular ... UniProt：O94905. Alternative Names：. ... <看更多>
gp78 uniprot 在 Human Erlin-2, ERLIN2 ELISA Kit - BT LAB 的相關結果
Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex (PubMed: 21343306). Involved in regulation of ... ... <看更多>
gp78 uniprot 在 E3 Ubiquitin-Protein Ligase AMFR (AMFR) Antibody - Abbexa 的相關結果
Purified by affinity chromatography using epitope-specific peptide. Storage, Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. UniProt Primary AC ... ... <看更多>
gp78 uniprot 在 Gene Ontology - TCDB » SEARCH 的相關結果
Ultimately, the E3 ligase gp78 ubiquitinates Cx32, targeting it for degradation. Thus, cells use a coordinated system of chaperones for membrane protein ... ... <看更多>
gp78 uniprot 在 Interaction mapping of endoplasmic reticulum ubiquitin ... 的相關結果
limiting enzymes such as HMGCoA reductase (HMGCR) by gp78/AMFR 32, ... amino acid sequences for all E3s and HCIPs were obtained from UniProt. ... <看更多>
gp78 uniprot 在 Anti-AMFR Antibody Picoband - Boster Bio 的相關結果
View all AMFR/gp78 Antibodies ... pb10039 2 IHC anti amfr gp78 picoband antibody ... Gene/Protein Information For AMFR (Source: Uniprot.org, NCBI) ... ... <看更多>
gp78 uniprot 在 Human Gene HMGCR (ENST00000680940.1) from ... 的相關結果
(from UniProt P04035) ... This INSIG1 binding leads to the recruitment of the ubiquitin ligase, AMFR/gp78, initiating ubiquitination of the reductase. ... <看更多>
gp78 uniprot 在 ERLIN2, 18% Sequence Identity to PDB 2rpb[1], chain A 的相關結果
Search for Structures, Proteins, Macromolecules, PDB, Uniprot, Features, Sequences, Genes, PSSH, HSSP. ... <看更多>
gp78 uniprot 在 Human Liver Cytochrome P450 3A4 Ubiquitination 的相關結果
Significance: This is the first mechanistic example of UBC7-gp78 ... b Residue numbers refer to UniProt sequences; accession numbers are as ... ... <看更多>
gp78 uniprot 在 INSIG1 - Cyclebase 3.0 的相關結果
... recruitment of the reductase to the ubiquitin ligase, AMFR/gp78. May play a role in growth and differentiation of tissues involved in metabolic control. ... <看更多>
gp78 uniprot 在 Anti-AMFR polyclonal antibody (CABT-BL272) 的相關結果
AMFR; autocrine motility factor receptor; gp78; RNF45; isoform 2; AMF receptor; AMF receptor isoform 1; AMF receptor isoform 2; AMFR; AMFR2_HUMAN; ... ... <看更多>
gp78 uniprot 在 phrog_9872 - PHROGS 的相關結果
PHROG prot ID NCBI prot ID NCBI prot annotation Virus ID (click to view) Virus na...
NC_024360_p168 YP_009043153.1 hypothetical protein NC_024360 Listeria...
DQ004855_p78 AAY53381.1 gp78 DQ004855 Listeria...
NC_024359_p146 YP_009042954.1 hypothetical protein NC_024359 Listeria... ... <看更多>
gp78 uniprot 在 Defining human ERAD networks through an integrative ... 的相關結果
E3s, gp78, Hrd1 and TEB4, share similar domain and topological ... protein names, known function, localisation, UNIPROT ID, and known yeast ... ... <看更多>
gp78 uniprot 在 Interaction mapping of endoplasmic reticulum ubiquitin ... - eLife 的相關結果
Both gp78 and RNF145 use Insig1/2 as adaptors to recruit and degrade HMGCR (Song ... N-linked glycosylation or disulphide bonds (UniProt). ... <看更多>
gp78 uniprot 在 anti-HMGCR antibody (ARG57991) 的相關結果
AMFR/gp78, initiating ubiquitination of the reductase. The ubiquitinated reductase is then extracted from the ER membrane and delivered to cytosolic 26S ... ... <看更多>
gp78 uniprot 在 ERLIN1 protein (human) - STRING interaction network 的相關結果
Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex. Involved in regulation of cellular ... ... <看更多>
gp78 uniprot 在 Results for the protein: Q9UKV5 - UMBC 的相關結果
NCBI, UniProt ... AltName: Full=Autocrine motility factor receptor; Short=AMF receptor; AltName: Full=RING finger protein 45; AltName: Full=gp78 ... ... <看更多>
gp78 uniprot 在 s41467-019-14085-2.pdf - Nature 的相關結果
ubiquitin-protein ligase gp78, a regulator of KAI1 degradation. ... Proteins were identified using a Uniprot human database from November. ... <看更多>
gp78 uniprot 在 An intrinsically disordered motif regulates the interaction ... 的相關結果
[AC] Q14CS0), and UFD1 (UniProt AC Q92890). (D) 15 N- 1 H correlation spectra of [U- 2 H, 13 C, 15 N]p97NTD illustrating site-specific cross-peak ... ... <看更多>
gp78 uniprot 在 Protein: P55072 | MoonDB v2.0 的相關結果
Uniprot : Necessary for the fragmentation of Golgi stacks during mitosis and ... Component of the VCP/p97-AMFR/gp78 complex that participates in the final ... ... <看更多>
gp78 uniprot 在 Interologous Interaction Database - I2D 的相關結果
Input Protein: Q14997, UniProt: Q14997, EntrezGene: 23198, UniGene: Hs.413801, CMHD: GeneCards: PSME4, Novus: Proteasome activator complex subunit 4; ... ... <看更多>
gp78 uniprot 在 Homo sapiens AMFR - HumanCyc 的相關結果
Synonyms, GP78; AUTOCRINE MOTILITY FACTOR RECEPTOR PRECURSOR; AMF RECEPTOR; autocrine motility factor receptor; ... Q9UKV5 (UniProt), Length, 63785 bp. ... <看更多>
gp78 uniprot 在 Gene: AMFR | I4326 | Homo sapiens autocrine motility factor ... 的相關結果
Gene Alias, GP78, RNF45. Description, Homo sapiens autocrine motility factor ... UniProt. GeneCard, AMFR. Chromosomal Position, 16q13. Homologene. SNP_Ref. ... <看更多>
gp78 uniprot 在 Table S2. - PLOS 的相關結果
3, Protein, Accession, Definition, Uniprot ID, Transmembrane domain (No,Yes) ... (AMF receptor) (gp78) - Homo sapiens (Human), AMFR2_HUMAN, Y, 0.33219 ... ... <看更多>
gp78 uniprot 在 A network of chaperones prevents and detects failures in ... 的相關結果
Ultimately, the E3 ligase gp78 ubiquitinates Cx32 proteins, targeting them for degradation. ... Enriched proteins are denoted with their Uniprot gene name. ... <看更多>
gp78 uniprot 在 Quantitative Assessment of Arsenite-Induced Perturbation of ... 的相關結果
The designed inserts for the construction of pLKO.1 vectors for the shRNA knockdown of GP78, HRD1, MARCH6, and TRC8 genes were annealed, ... ... <看更多>
gp78 uniprot 在 EVI/WLS function is regulated by ubiquitination and linked to ... 的相關結果
notably HRD1, GP78, and MARCH6, which have well-studied orthologs in yeast (Lopata et ... FAF2, UBXN4 and UBE2K according to UniProt identifiers: O94905,. ... <看更多>
gp78 uniprot 在 how to extract only the type of the membrane protein,from its ... 的相關結果
That matters, because for your first mentioned protein UniProt will tell you: ... autocrine motility factor receptor precursor (amf receptor) (gp78). ... <看更多>
gp78 uniprot 在 Erratum to “Modulation of ERQC and ERAD - Hindawi 的相關結果
The transmembrane helix of MmMOGS (mouse GCS1, UniProt Q80UM7, MOGS_MOUSE, ... Another ERAD E3 enzyme, AMFR (aka gp78), mediates tumour invasion and ... ... <看更多>
gp78 uniprot 在 ERLIN2 Antibody - Cepham Life Sciences Research Products 的相關結果
Promotes sterol-accelerated ERAD of HMGCR probably implicating an AMFR/gp78-containing ubiquitin ligase complex (PubMed:21343306). Involved in regulation of ... ... <看更多>
gp78 uniprot 在 ERLIN2 Antibody, Biotin conjugated - Assay Genie 的相關結果
AMFR/gp78-containing ubiquitin ligase complex. ... Uniprot. O94905. Synonyms: Erlin-2 (Endoplasmic reticulum lipid raft-associated protein 2) ... ... <看更多>
gp78 uniprot 在 E3 ubiquitin-protein ligase AMFR - Homo sapiens (Human) 的相關結果
The VCP/p97-AMFR/gp78 complex is involved in the sterol-accelerated ERAD degradation of HMGCR through binding to the HMGCR-INSIG1 complex at the ER membrane ( ... ... <看更多>