Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase. Molecular ... ... <看更多>
「gp78 gene」的推薦目錄：
gp78 gene 在 E3 ubiquitin-protein ligase AMFR - Homo sapiens (Human) 的相關結果
The VCP/p97-AMFR/gp78 complex is involved in the sterol-accelerated ERAD degradation of HMGCR through binding to the HMGCR-INSIG1 complex at the ER membrane ( ... ... <看更多>
gp78 gene 在 AMFR 的相關結果
"The gene product of the gp78/AMFR ubiquitin E3 ligase cDNA is selectively recognized by the 3F3A antibody within a subdomain of the endoplasmic reticulum". ... <看更多>
gp78 gene 在 A gp78/AMFR protein-driven gene signature that predicts ... 的相關結果
Conclusions: Our results show that gp78/AMFR is an independent predictor of bc survival and response to therapy, based on race, thus implicating ... ... <看更多>
gp78 gene 在 RETRACTED ARTICLE: A novel polymorphism of the GP78 ... 的相關結果
The aim of the present study was to assess the association between the human gp78 gene polymorphism and coronary artery disease (CAD) in a Han ... ... <看更多>
gp78 gene 在 gp78 Gene Set 的相關結果
Symbol, Name. AMFR, autocrine motility factor receptor, E3 ubiquitin protein ligase. APOB, apolipoprotein B. ATXN3, ataxin 3. CD82, CD82 molecule. ... <看更多>
gp78 gene 在 AMFR protein expression summary 的相關結果
Official gene symbol, which is typically a short form of the gene name, according to HGNC. AMFR (gp78, RNF45). Protein class i. ... <看更多>
gp78 gene 在 AUTOCRINE MOTILITY FACTOR RECEPTOR; AMFR - OMIM 的相關結果
603243 - AUTOCRINE MOTILITY FACTOR RECEPTOR; AMFR - GP78 - AMFR. ... GP78. HGNC Approved Gene Symbol: AMFR ... Gene-Phenotype Relationships ... ... <看更多>
gp78 gene 在 Induction via Functional Protein Stabilization of Hepatic ... 的相關結果
Liver specific gp78/AMFR genetic ablation results in functional protein ... Relative gene expression level of each P450 was determined by ... ... <看更多>
gp78 gene 在 Protein expression of the gp78 E3 ligase predicts poor ... 的相關結果
( B ) Volcano plot of patient gp78 gene modules scores and other gene signature scores in patients with residual versus pCR (log2 residual ... ... <看更多>
gp78 gene 在 The E3 Ubiquitin Ligase gp78 Protects against ER Stress ... 的相關結果
gp78 is a polytopic RING (really interesting new gene) finger protein in the ER (Shimizu et al., 1999, Ponting, 2000, Fang et al., 2001). ... <看更多>
gp78 gene 在 GP78 siRNA and shRNA Plasmids (m) 的相關結果
GP78 siRNA (m), shRNA and Lentiviral Particle Gene Silencers designed to knockdown mouse GP78 gene expression. Cited in 1 publications. ... <看更多>
gp78 gene 在 AMFR (autocrine motility factor receptor) 的相關結果
ALIAS. GP78,RNF45 ; FUSION GENES. Show Gene Fusions ; Description. AMFR belongs to the family of RING-Finger ubiquitin ligases. The complete ... ... <看更多>
gp78 gene 在 Gp78-derived gene modules predict pCR and cluster ... 的相關結果
(A) Hierarchical clustering of patient scores based on gp78 modules and other predictive modules. (B) Volcano plot of patient gp78 gene modules scores and ... ... <看更多>
gp78 gene 在 The tumor autocrine motility factor receptor, gp78, is a ... 的相關結果
Sex-chromosome dosage (SCD) effects on human gene expression are central to the biology of sex differences and sex-chromosome aneuploidy syndromes but are ... ... <看更多>
gp78 gene 在 Gp78, an ER associated E3, promotes SOD1 and ataxin-3 ... 的相關結果
Mammalian gp78 is an E3 ubiquitin ligase involved in ER-associated degradation (ERAD). Here, we show that gp78 interacts with both SOD1 and ataxin-3. ... <看更多>
gp78 gene 在 Gp78, an E3 Ubiquitin Ligase Acts as a Gatekeeper ... 的相關結果
Others have reported that gp78 might ubiquitinate certain folded proteins and may function as a metabolic regulator of genes such as HMG-CoA reductase (HMGCR) ... ... <看更多>
gp78 gene 在 AMFR | Cancer Genetics Web 的相關結果
Gene : AMFR; autocrine motility factor receptor. Aliases: GP78, RNF45. Location: 16q13. Summary: This locus encodes a glycosylated transmembrane receptor. ... <看更多>
gp78 gene 在 Induction via Functional Protein Stabilization of Hepatic ... 的相關結果
Liver-specific gp78/AMFR genetic ablation results in functional protein ... Relative gene expression level of each P450 was determined by ... ... <看更多>
gp78 gene 在 Expression of Gp78/Autocrine Motility Factor Receptor and ... 的相關結果
Elevated levels of Gp78/AMFR expression and AMF internalization in ... RT was used for PCR amplification for each sample and marker gene. ... <看更多>
gp78 gene 在 Plasmids related to Amfr 的相關結果
ID Plasmid Gene/Insert PI
185344 pEGFP‑C1‑G2BRgp78 gp78 aa 574‑600 (G2BR) (Homo sapiens) Weiss...
123591 pCMV‑N‑HA‑Gp78 autocrine motility factor receptor (Mus musculus) Beutler
123590 pcDNA6‑N‑3XFLAG‑Gp78 autocrine motility factor receptor (Mus musculus) Beutler ... <看更多>
gp78 gene 在 The E3 Ubiquitin Ligase gp78 Protects against ER ... - NSF PAR 的相關結果
The gp78 cDNA was isolated from zebrafish larvae at 5 dpf. (days post fertilization) by RT-PCR. The zebrafish gp78 gene encodes a protein of 620 amino acids ... ... <看更多>
gp78 gene 在 GW26-e2168 A Novel Polymorphism of the GP78 Gene is ... 的相關結果
The aim of the present study was to assess the association between the human gp78 gene polymorphism and type 2 diabetes mellitus (T2DM) in a Han ... ... <看更多>
gp78 gene 在 Amfr MGI Mouse Gene Detail - autocrine motility factor receptor 的相關結果
gp78. Feature Type. protein coding gene. IDs. MGI:1345634. NCBI Gene: 23802. Alliance. gene page. Transcription Start Sites. 5 TSS. Location & ... <看更多>
gp78 gene 在 AMFR/gp78 Research Products 的相關結果
AMFR/gp78 products available through Novus Biologicals. ... AMFR/gp78 Proteins (2) ... Discover related pathways, diseases and genes to AMFR/gp78. ... <看更多>
gp78 gene 在 tcna1927 AMFR Antibody / GP78 的相關結果
Western blot analysis of AMFR antibody and 293 cell lysate (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the AMFR gene (2). ... <看更多>
gp78 gene 在 Human Gene AMFR (ENST00000290649.10) from ... 的相關結果
-; AltName: Full=Autocrine motility factor receptor; Short=AMF receptor; AltName: Full=RING finger protein 45; AltName: Full=gp78; FUNCTION: E3 ubiquitin- ... ... <看更多>
gp78 gene 在 AMFR - autocrine motility factor receptor, E3... 的相關結果
The gene product of the gp78/AMFR ubiquitin E3 ligase cDNA is selectively recognized by the 3F3A antibody within a subdomain of the endoplasmic reticulum ... ... <看更多>
gp78 gene 在 The sterol-responsive RNF145 E3 ubiquitin ligase ... 的相關結果
... genome-wide screens using sterol-sensitive endogenous HMG-CoA reductase (HMGCR) reporter identify the sterol-responsive RNF145 and gp78 ... ... <看更多>
gp78 gene 在 Rabbit Polyclonal Anti-AMFR Antibody - Buy for research 的相關結果
References (2). Recommended Applications. Product Description. Polyclonal Antibody against Human AMFR. Alternative Gene Names. gp78, RNF45. ... <看更多>
gp78 gene 在 Basal Gp78-dependent mitophagy promotes mitochondrial ... 的相關結果
Gp78 degradation of outer mitochondrial membrane proteins form ... A Schematic showing Exon 1 region of Gp78 gene on chromosome 16 and ... ... <看更多>
gp78 gene 在 GP78 gene polymorphism is associated with coronary heart ... 的相關結果
Objective To evaluate potential association between human GP78 gene an... ... genotype and T allele of rs2617849 functions as a genetic markers of CHD． ... <看更多>
gp78 gene 在 KEGG ORTHOLOGY: K10636 的相關結果
K10636 AMFR, GP78; E3 ubiquitin-protein ligase AMFR 09180 Brite Hierarchies 09182 Protein families: genetic information processing 04121 Ubiquitin system ... <看更多>
gp78 gene 在 Gene: AMFR (ENSG00000159461) - Summary 的相關結果
Gene Synonyms. RNF45, gp78. Location. Chromosome 16: 56,361,452-56,425,545 reverse strand. GRCh38:CM000678.2. About this gene. This gene has 12 transcripts ... ... <看更多>
gp78 gene 在 Symbol report for AMFR 的相關結果
HGNC:463. Symbol status. Approved. Alias symbols. RNF45. gp78. Chromosomal location. 16q13. Gene groups. Ring finger proteins. Gene resources for AMFR. ... <看更多>
gp78 gene 在 Anti-GP78 Antibody Products 的相關結果
GP78 is a reported alias name for the human gene AMFR, or 'autocrine motility factor receptor'. The 643-amino acid protein has a reported mass of ... ... <看更多>
gp78 gene 在 Autocrine motility factor receptor, e3 ubiquitin protein ligase 的相關結果
CYP3A4 ubiquitination by gp78 (the tumor autocrine motility factor ... The gene product of the gp78/AMFR ubiquitin E3 ligase cDNA is ... ... <看更多>
gp78 gene 在 Abstract 6141: Understanding the role of gp78 in breast ... 的相關結果
The purpose of this research was to understand how gp78 is associated with poor survival rates by studying tumor biology and gene expression ... ... <看更多>
gp78 gene 在 Retraction Note: A novel polymorphism of the GP78 gene ... 的相關結果
A novel polymorphism of the GP78 gene is associated with coronary artery disease in Han population in China. Lipids Health Dis, v.13, p.147, 2014, Cha E et al. ... <看更多>
gp78 gene 在 AUTOCRINE MOTILITY FACTOR-RECEPTOR IN HUMAN ... 的相關結果
No difference in gene structure or copy number was found among the three cell lines and all expressed gp78. Cell surface distribution and level ... ... <看更多>
gp78 gene 在 Genetic variation of RNF145 gene and blood lipid levels in ... 的相關結果
& DeBose-Boyd, R. A. Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to ... ... <看更多>
gp78 gene 在 AMFR / E3 Ubiquitin-Protein Ligase AMFR Recombinant ... 的相關結果
... Autocrine motility factor receptor; AMF receptor; RING finger protein 45; RING-type E3 ubiquitin transferase AMFR; gp78; RNF45. Product Gene Name ... ... <看更多>
gp78 gene 在 The GR-gp78 Pathway is involved in Hepatic Lipid ... 的相關結果
Although genetic and dietary models for fatty liver disease have revealed a critical relationship between hepatic steatosis and 11β-HSD1 ... ... <看更多>
gp78 gene 在 AMFR (autocrine motility factor receptor) | Gene Report 的相關結果
Aliases: GP78, RNF45. Genome Location: chr16:56361452-56425545 (hg38). Function: Molecular Function. ubiquitin-protein transferase activity (GO:0004842) ... ... <看更多>
gp78 gene 在 gp78: a Multifaceted Ubiquitin Ligase that Integrates ... 的相關結果
The endoplasmic reticulum (ER) is the site for maturation of proteins destined for the secretory pathway. Failure in maturation leads to production of mis. ... <看更多>
gp78 gene 在 Rabbit anti-gp78 Antibody 的相關結果
Autocrine motility factor is a tumor motility-stimulating protein secreted by tumor cells. Gene ID: 267. Gene Symbol: AMFR. Gene Name: ... ... <看更多>
gp78 gene 在 Protein expression of the gp78 E3 ligase predicts poor ... 的相關結果
Furthermore, gene expression signatures, derived from patients stratified by gp78 protein expression, are strong predictors of recurrence and pathological ... ... <看更多>
gp78 gene 在 Purification of human tumor cell autocrine motility factor ... 的相關結果
glycoprotein (gp78), suggesting protein kinase partic- ipation in migratory signal transduction. The gene encoding gp78 was cloned from an ... ... <看更多>
gp78 gene 在 AMFR/GP78 antibody (16675-1-AP) 的相關結果
Cited in 24 publications. AMFR/GP78 antibody for IF, IP, WB, ELISA and reacts with human, mouse, rat. ... Gene symbol, AMFR. Gene ID (NCBI), 267. ... <看更多>
gp78 gene 在 Anti-Glycoprotein 78 Antibody, clone 3F3A | MABC949 的相關結果
Anti-Glycoprotein 78 Antibody, clone 3F3A Detect GP78 using this rat ... 45) is encoded by the RNF45 (also known as AMFR) gene (Gene ID 267) in human. ... <看更多>
gp78 gene 在 Induction via Functional Protein Stabilization of Hepatic ... 的相關結果
Cytochromes P450 upon gp78/Autocrine Motility Factor. Receptor (AMFR) Ubiquitin E3-Ligase Genetic Ablation in Mice:. ... <看更多>
gp78 gene 在 Protein expression of the gp78 E3 ligase predicts poor ... 的相關結果
Furthermore, gene expression signatures, derived from patients stratified by gp78 protein expression, are strong predictors of recurrence ... ... <看更多>
gp78 gene 在 Showing Protein E3 ubiquitin-protein ligase AMFR ... 的相關結果
IdentificationBiological propertiesGene propertiesProtein propertiesExternal ... Autocrine motility factor receptor, isoform 2; RING finger protein 45; gp78. ... <看更多>
gp78 gene 在 GP78 / AMFR 的相關結果
Gene Name: autocrine motility factor receptor, E3 ubiquitin protein ligase. Synonyms: AMFR, AMF receptor, isoform 1, AMF receptor, ... ... <看更多>
gp78 gene 在 p38 MAP kinase–dependent phosphorylation of the Gp78 ... 的相關結果
Gp78 is localized throughout the ER; however, the anti-Gp78 3F3A ... The gene product of the gp78/AMFR ubiquitin E3 ligase cDNA is ... ... <看更多>
gp78 gene 在 Protein Folding and Quality Control in the ER 的相關結果
(D) gp78 ligase complex: The carboxyl terminus of gp78 is composed of four motifs: ... Trafficking of the human ether-a-go-go-related gene (hERG) potassium ... ... <看更多>
gp78 gene 在 AMFR protein (human) - STRING interaction network 的相關結果
AMFR Neighborhood Gene Fusion
Predicted Functional Partners: Predicted Functional Partners: Neighborhood Gene Fusion
UBE2G2
VCP ... <看更多>
gp78 gene 在 Human AMFR/gp78 (NP_001135) VersaClone cDNA 的相關結果
Background: AMFR/gp78. Long Name. Autocrine Motility Factor Receptor. Entrez Gene IDs. 267 (Human); 23802 (Mouse); 361367 (Rat). Alternate Names. ... <看更多>
gp78 gene 在 Ubiquitin Ligases in Cholesterol MetabolismUbiquitin ... 的相關結果
Human glycoprotein 78 (gp78) is a 643 aa. protein which is composed of ... insulin-induced gene 1 and 2 proteins (Insig-1/2, or Insigs), ... ... <看更多>
gp78 gene 在 UBE2G2 (Ubc7) [6His-tagged] 20 µg 的相關結果
The UBE2G2 gene is 2.9-kb and encodes a 165-amino-acid protein that shares 57% ... Binding of UBE2G2 to the E3 ligase GP78 via the G2BR domain significantly ... ... <看更多>
gp78 gene 在 含EB病毒膜蛋白gp350/220、gp85、gp78、gp25基因的重组 ... 的相關結果
根据gene bank公布的EBV膜蛋白gp350/220基因序列(gene bank查询号AY961628.3)，设计PCR引物如下：. 上游引物P1：TTGAGTCGACACCATGGAGGCAGCCTTGCTTGT；. 下游引物P2： ... ... <看更多>
gp78 gene 在 The gene product of the gp78/AMFR ubiquitin E3 ligase cDNA is ... 的相關結果
We show here that the gp78/AMFR gene product is indeed recognized by the 3F3A mAb. The FLAG-tagged AMFR immunoprecipitated with an anti-FLAG antibody was ... ... <看更多>
gp78 gene 在 The E3 Ubiquitin Ligase gp78 Protects against ER Stress ... 的相關結果
The E3 Ubiquitin Ligase gp78 Protects against ER Stress in Zebrafish Liver · Genes / Markers. Marker, Marker Type, Name · Expression. Gene, Antibody, Fish ... ... <看更多>
gp78 gene 在 AMFR Antibodies, cDNA Clones Research Reagents 的相關結果
AMFR is also known as GP78 and RNF45. The human AMFR gene encodes a 72996 Da protein containing 643 amino acids. The AMFR protein is ubiquitously expressed ... ... <看更多>
gp78 gene 在 Variant Detail : MGeND 的相關結果
<0.001, Coronary Arteriosclerosis, A novel polymorphism of the GP78 gene is associated with coronary artery disease... BeFree, 25200441 · Detail. ... <看更多>
gp78 gene 在 The mechanism of gp78 ubiquitin ligase in suppressing ... 的相關結果
Here we report the identification of MYBL2 as a novel gp78 substrate. MYBL2 is a transcription factor that activates multiple genes whose protein products ... ... <看更多>
gp78 gene 在 Role and Regulation of Gp78 E3 Ubiquitin Ligase and its ... 的相關結果
Gene analysis of Gp78 reveals it is a protein of 648 amino acid with an estimated 7 transmembrane domains (Shimizu et al., 1999). ... <看更多>
gp78 gene 在 Ubiquitin-mediated regulation of the E3 ligase GP78 by ... 的相關結果
In addition, it is also targeted for proteasomal degradation by HRD1 and in turn affects the levels of insulin-induced gene-1 (Insig-1) (Ballar et al.,. 2010; ... ... <看更多>
gp78 gene 在 Polyubiquitylation of AMF requires cooperation between ... 的相關結果
Keywords: protein ubiquitylation, ubiquitin ligase, AMF, gp78, TRIM25 ... insulin-induced gene-1 and apoplipoprotein B [20-22], ... ... <看更多>
gp78 gene 在 GP78 Cooperates with Dual-Specificity Phosphatase 1 To ... 的相關結果
Subsequent studies showed that GP78 is an E3 ligase that belongs to the RING (really interesting new gene) E3 ubiquitin ligase family (2). ... <看更多>
gp78 gene 在 AMFR Polyclonal Antibody (PA5-29501) 的相關結果
The protein encoded by this gene is a glycosylated transmembrane protein and a receptor for autocrine motility factor. ... Gene Aliases: AMFR; GP78; RNF45. ... <看更多>
gp78 gene 在 2LVN: Structure of the gp78 CUE domain 的相關結果
Structure of the gp78 CUE domain. ... RING finger ubiquitin ligase (E3) gp78 regulates critical proteins via the ... Gene Names: AMFR, RNF45 ... <看更多>
gp78 gene 在 Attempts to Understand Metastasis Formation II: Regulatory ... 的相關結果
1990), in the case of gp78 consisting of three domains linked by conserved ... divergence of these two proteins from a common ancestral gene, however. ... <看更多>
gp78 gene 在 gp78: a multifaceted ubiquitin ligase that integrates a unique ... 的相關結果
gp78 : a multifaceted ubiquitin ligase that integrates a unique protein degradation pathway from the endoplasmic reticulum (English). edit. 1 reference. ... <看更多>
gp78 gene 在 AACR 2022 Proceedings: Part A Online-Only and April 10 的相關結果
A signature representing the gene-set was significantly associated with poor ... #6141 Understanding the role of gp78 in breast cancer health disparities. ... <看更多>
gp78 gene 在 Clinical Molecular Diagnostics - 第 846 頁 - Google 圖書結果 的相關結果
of the tumor cell genes, that is, there are differences in inva- sion and ... of gp78 positive patients is significantly lower than that of negative ones. ... <看更多>
gp78 gene 在 Cancer Metastasis — Related Genes - 第 112 頁 - Google 圖書結果 的相關結果
The receptor for AMF has been identified as 78 kDa cell surface glycoprotein designated gp78. A role for AMFR in the metastatic process was first suggested ... ... <看更多>
gp78 gene 在 AMFR autocrine motility factor receptor [ (human)] 的相關結果
gp78 is expressed specifically in human prostate cancer rather than normal prostate tissues, it could be a putative biomarker for prostate ... ... <看更多>