由 M Schröder 著作 · 2005 · 被引用 51 次 — The so-called orotate pathway of pyrimidine de novo synthesis is defined as the formation of UMP from carbamoyl phosphate, Asp, and phosphoribosyl pyrophosphate ... ... <看更多>
「de novo pyrimidine synthesis」的推薦目錄：
de novo pyrimidine synthesis 在 7.10: Pyrimidine de novo Biosynthesis - Biology LibreTexts 的相關結果
7.10: Pyrimidine de novo Biosynthesis ... ATCase is regulated by three compounds. One of these (aspartate) is a substrate and it activates the ... ... <看更多>
de novo pyrimidine synthesis 在 Enzymatic De Novo Pyrimidine Nucleotide Synthesis 的相關結果
Enzymatic synthesis offers an efficient and flexible means to synthesize nucleoside triphosphates from a variety of commercially available ... ... <看更多>
de novo pyrimidine synthesis 在 De Novo Pyrimidine Nucleotide Synthesis Mainly Occurs ... 的相關結果
Nucleotide de novo synthesis is highly conserved among organisms and represents an essential biochemical pathway. In plants, the two initial enzymatic ... ... <看更多>
de novo pyrimidine synthesis 在 Purine and Pyrimidine Nucleotide Synthesis and Metabolism 的相關結果
The de novo pathway leading to the synthesis of AMP and GMP begins with the transfer of an amido group from glutamine to PRPP (Figure 1). Since ... ... <看更多>
de novo pyrimidine synthesis 在 Inhibition of the de novo pyrimidine biosynthesis ... - PLOS 的相關結果
由 MC Lafita-Navarro 著作 · 2020 · 被引用 13 次 — Both purines and pyrimidines can be synthesized by 2 alterative pathways: the de novo pathways that metabolize ribose and amino acids in a ... ... <看更多>
de novo pyrimidine synthesis 在 Genes of De Novo Pyrimidine Biosynthesis from the ... 的相關結果
Genes of De Novo Pyrimidine Biosynthesis from the Hyperthermoacidophilic Crenarchaeote Sulfolobus acidocaldarius: Novel Organization in a ... ... <看更多>
de novo pyrimidine synthesis 在 Small-Molecule Screen Identifies De Novo Nucleotide ... 的相關結果
Furthermore, we found that SIRT3 inhibits glutamine metabolism and de novo nucleotide synthesis. Mechanistically, loss of SIRT3 promotes de novo ... ... <看更多>
de novo pyrimidine synthesis 在 Pyrimidine metabolism - Wikipedia 的相關結果
De novo biosynthesis of pyrimidine ... ... <看更多>
de novo pyrimidine synthesis 在 De Novo Nucleotide Synthesis - Biochemistry - Medbullets ... 的相關結果
De Novo Nucleotide Synthesis · sugar building block formed in nucleotide synthesis. added to nitrogenous base to form nucleoside · formed from ... ... <看更多>
de novo pyrimidine synthesis 在 Stimulation of de Novo Pyrimidine Synthesis by ... - Science 的相關結果
Activation of mTORC1 led to the acute stimulation of metabolic flux through the de novo pyrimidine synthesis pathway. mTORC1 signaling posttranslationally ... ... <看更多>
de novo pyrimidine synthesis 在 Key steps involved in de novo pyrimidine synthesis and purine... 的相關結果
Download scientific diagram | Key steps involved in de novo pyrimidine synthesis and purine synthesis. Biochemicals in boxes are metabolites identified in ... ... <看更多>
de novo pyrimidine synthesis 在 De novo pyrimidine biosynthesis is required for virulence of ... 的相關結果
gondii tachyzoites, which suggests that the de novo pyrimidine biosynthesis pathway may be necessary for growth. We have examined the virulence ... ... <看更多>
de novo pyrimidine synthesis 在 Mitochondrial-Linked De Novo Pyrimidine Biosynthesis ... 的相關結果
Mitochondrial-Linked De Novo Pyrimidine Biosynthesis Dictates Human T-Cell Proliferation but Not Expression of Effector Molecules. ... <看更多>
de novo pyrimidine synthesis 在 de novo synthesis of pyrimidine ribonucleotides - DAV University 的相關結果
De novo pyrimidine nucleotide biosynthesis proceeds in a somewhat different manner from purine nucleotide synthesis; the six-membered pyrimidine ring is made ... ... <看更多>
de novo pyrimidine synthesis 在 CAD: A Multifunctional Protein Leading De Novo Pyrimidine ... 的相關結果
Abstract Pyrimidines are essential precursors for DNA (deoxyribonucleic acid) and RNA (ribonucleic acid) synthesis, protein glycosylation ... ... <看更多>
de novo pyrimidine synthesis 在 Pyrimidine Biosynthetic Enzyme CAD: Its Function, Regulation ... 的相關結果
In cancer cells, adaptive transformation from the salvage pathway into the de novo pyrimidine synthesis pathway benefits their high nucleotide requirement for ... ... <看更多>
de novo pyrimidine synthesis 在 Adaptive Reprogramming of De Novo Pyrimidine Synthesis Is ... 的相關結果
Pharmacologic inhibition of de novo pyrimidine synthesis sensitizes TNBC cells to genotoxic chemotherapy agents by exacerbating DNA damage. Moreover, combined ... ... <看更多>
de novo pyrimidine synthesis 在 de novo pyrimidine biosynthetic pathwayRat Genome Database 的相關結果
Mammalian de novo pyrimidine biosynthesis is accomplished by six enzymatic activities, encoded by only three genes - two encode multifunctional proteins. ... <看更多>
de novo pyrimidine synthesis 在 Mammalian Pyrimidine Biosynthesis: Fresh Insights into an ... 的相關結果
1The de novo pyrimidine biosynthetic pathway, steps 1-6, and the subsequent formation of CTP. UTP is formed from UMP by sequential reactions ... ... <看更多>
de novo pyrimidine synthesis 在 Pyrimidine metabolism: de novo synthesis of UMP - Reactome ... 的相關結果
The events of pyrimidine metabolism are conveniently if somewhat arbitrarily grouped into four pathways: de novo synthesis of uridine 5'-monophosphate (UMP) ... ... <看更多>
de novo pyrimidine synthesis 在 Saccharomyces cerevisiae de novo biosynthesis of pyrimidine ... 的相關結果
cerevisiae, the initial steps of de novo pyrimidine biosynthesis are catalyzed by the bifunctional carbamoylphosphate synthetase/aspartate transcarbamylase ... ... <看更多>
de novo pyrimidine synthesis 在 Restriction of De Novo Pyrimidine Biosynthesis Inhibits Th1 ... 的相關結果
Notably, the inhibition of de novo pyrimidine biosynthesis by leflunomide promoted Th2 cell differentiation from uncommitted precursors in vitro ... ... <看更多>
de novo pyrimidine synthesis 在 Purines and Pyrimidines Question 6 的相關結果
The correct answer is in bold. The major control of de novo pyrimidine nucleotide synthesis in man is: A. feedback inhibition of glutamine-PRPP amidotransferase ... ... <看更多>
de novo pyrimidine synthesis 在 Inhibition of De Novo Pyrimidine Nucleotide Synthesis By the ... 的相關結果
Background: Pyrimidine nucleotides are generated either by de novo synthesis or the salvage pathway in which pyrimidine nucleotides are ... ... <看更多>
de novo pyrimidine synthesis 在 [PDF] Functional Analysis of the Pyrimidine de Novo Synthesis ... 的相關結果
It is concluded that reduced pyrimidine de novo synthesis is compensated for by reduction in growth rates, and the remaining nucleotide ... ... <看更多>
de novo pyrimidine synthesis 在 De Novo Pyrimidine Synthesis is a Targetable ... - bioRxiv 的相關結果
Through a chemical synthetic lethality screen, we discovered that IDH1 mutant glioma cells are hypersensitive to drugs targeting enzymes in the ... ... <看更多>
de novo pyrimidine synthesis 在 De novo pyrimidine synthesis is necessary for ... - eScholarship 的相關結果
De novo pyrimidine synthesis is necessary for intestinal colonization of Salmonella Typhimurium in chicks. 2017. Author(s): Yang, Hee-Jeong;; Bogomolnaya, Lydia ... ... <看更多>
de novo pyrimidine synthesis 在 MetaCyc superpathway of pyrimidine ribonucleotides de novo ... 的相關結果
The pyrimidine nucleotide de novo biosynthetic pathway derives in part from the central metabolic precursors oxaloacetate and D-ribose 5-phosphate. L-aspartate, ... ... <看更多>
de novo pyrimidine synthesis 在 Inhibition of the de novo pyrimidine biosynthesis pathway ... 的相關結果
In this study, we show that enzymes necessary for the de novo biosynthesis of pyrimidines, DHODH and UMPS, are elevated in high grade gliomas ... ... <看更多>
de novo pyrimidine synthesis 在 The Synthesis and Degradation of Nucleotides 的相關結果
Nearly all organisms can make the purine and pyrimidine nucleotides via so-called de novo biosynthetic pathways. (De novo means “anew”; a less literal but more ... ... <看更多>
de novo pyrimidine synthesis 在 Initial Steps in the de novo Pyrimidine Biosynthesis in Ascaris ... 的相關結果
1954). On the other hand the origin of the carbamyl phosphate needed for the de novo synthesis of pyrimidines is still a question of interest. ... <看更多>
de novo pyrimidine synthesis 在 QuickGO::Term GO:0006207 的相關結果
'de novo' pyrimidine base biosynthetic process, exact. 'de novo' pyrimidine base synthesis, exact. 'de novo' pyrimidine base formation, exact. ... <看更多>
de novo pyrimidine synthesis 在 De Novo Pyrimidine Synthesis Mnemonic for USMLE - Pixorize 的相關結果
De Novo Pyrimidine Synthesis describes the biochemical pathway used to make pyrimidine nucleotides from building blocks in the cell. Pyrimidine Synthesis begins ... ... <看更多>
de novo pyrimidine synthesis 在 pyrimidine nucleotide de novo biosynthesis - CORE 的相關結果
De novo pyrimidine nucleotide metabolism is a central component of all free-living cells, occupying an essential position relative to metabolic processes ... ... <看更多>
de novo pyrimidine synthesis 在 Purines and pyrimidines - Knowledge @ AMBOSS 的相關結果
Pyrimidine nucleotides are also newly synthesized or recovered. However, in contrast to de novo synthesis of purine nucleotides, the basic ring ... ... <看更多>
de novo pyrimidine synthesis 在 Enzymatic de novo pyrimidine nucleotide synthesis - Scripps ... 的相關結果
Enzymatic synthesis offers an efficient and flexible means to synthesize nucleoside ... Here, we recapitulate de novo pyrimidine biosynthesis in vitro, ... ... <看更多>
de novo pyrimidine synthesis 在 Inhibition of de novo pyrimidine synthesis augments ... 的相關結果
De Novo pyrimidine synthesis is a mechanism of Gemcitabine (Gem) resistance in pancreatic cancer. This study aims to assess the efficacy and changes in the ... ... <看更多>
de novo pyrimidine synthesis 在 De Novo Synthesis of Pyrimidine Nucleotides (2) 的相關結果
Nucleotide Biosynthesis. Nucleotides can be synthesized de novo (“from the beginning”) from amino acids, ribose-5-phosphate, CO2, and NH3. ... <看更多>
de novo pyrimidine synthesis 在 CAD, A Multienzymatic Protein at the Head of de Novo ... 的相關結果
novo biosynthesis of pyrimidine nucleotides: glutamine-dependent Carbamoyl ... proving that de novo pyrimidine synthesis is required for cell proliferation ... ... <看更多>
de novo pyrimidine synthesis 在 Critical importance of the de novo pyrimidine biosynthesis ... 的相關結果
However, the requirement of de novo pyrimidine biosynthesis for parasite growth and survival has not yet been elucidated. Carbamoyl-phosphate synthetase II ... ... <看更多>
de novo pyrimidine synthesis 在 Critical Roles of Glutamine as Nitrogen Donors in Purine and ... 的相關結果
of purine nucleotides and two enzymes involved in the de novo synthesis of pyrimidine nucleotides. In this review, the specific roles of glutamine in the de ... ... <看更多>
de novo pyrimidine synthesis 在 Enzymatic De Novo Pyrimidine Nucleotide Synthesis,Journal ... 的相關結果
Enzymatic synthesis offers an efficient and flexible means to synthesize nucleoside ... Here, we recapitulate de novo pyrimidine biosynthesis in vitro, ... ... <看更多>
de novo pyrimidine synthesis 在 Broad-spectrum antiviral that interferes with de novo ... - PNAS 的相關結果
Broad-spectrum antiviral that interferes with de novo pyrimidine biosynthesis. Hans-Heinrich Hoffmann, Andrea Kunz, Viviana A. ... <看更多>
de novo pyrimidine synthesis 在 De Novo Pyrimidine Synthesis is a Targetable ... - Newswise 的相關結果
AbstractMutations affecting isocitrate dehydrogenase (IDH) enzymes are prevalent in glioma, leukemia, and other cancers. ... <看更多>
de novo pyrimidine synthesis 在 Homo sapiens UTP and CTP de novo biosynthesis - HumanCyc 的相關結果
The de novo pyrimidine nucleotide biosynthetic pathway (see UMP biosynthesis I) converts hydrogencarbonate, L-glutamine, L-aspartate and ... ... <看更多>
de novo pyrimidine synthesis 在 MetaCyc UMP biosynthesis - Trypanocyc 的相關結果
In addition to de novo biosynthesis, salvage pathways reutilize exogenous free bases and nucleosides and some of the resulting pyrimidine nucleotides can ... ... <看更多>
de novo pyrimidine synthesis 在 Targeting de Novo Pyrimidine Biosynthesis by Leflunomide for ... 的相關結果
Targeting de Novo Pyrimidine Biosynthesis by Leflunomide for the Treatment of COVID-19 Virus Disease (DEFEAT-COVID) · No Intervention: Standard ... ... <看更多>
de novo pyrimidine synthesis 在 Inhibition of De Novo Pyrimidine Synthesis Depletes Acute ... 的相關結果
De novo nucleotide synthesis is necessary to meet the enormous demand for nucleotides, other macromolecules associated with acute myeloid leukemia (AML) ... ... <看更多>
de novo pyrimidine synthesis 在 De novo pyrimidine nucleotide synthesis mainly occurs outside of ... 的相關結果
Nucleotide de novo synthesis is highly conserved among organisms and represents an essential biochemical pathway. In plants, the two initial enzymatic ... ... <看更多>
de novo pyrimidine synthesis 在 Antiviral Activity of Inhibitors of Pyrimidine De-Novo Biosynthesis 的相關結果
The effects of inhibitors of the de-novo pathway of pyrimidine biosynthesis on HCMv viral replication- were quantified by DNA dot blot. All pyrimidine. ... <看更多>
de novo pyrimidine synthesis 在 Purine & Pyrimidine Synthesis (de-novo) - Easy Biology Class 的相關結果
I. De-novo synthesis (synthesis from scratch): it is a biochemical pathway in which nucleotides are synthesized new from simple precursor molecules. ... <看更多>
de novo pyrimidine synthesis 在 Nucleotide Synthesis (De-novo and Salvage Pathways of ... 的相關結果
PPT on Nucleic Acid Biosynthesis. De-novo and Salvage Pathways of Nucleotides. Nucleotide Metabolism. Biosynthesis of Purine. Biosynthesis of Pyrimidine. ... <看更多>
de novo pyrimidine synthesis 在 De Novo Pyrimidine Nucleotide Synthesis ... - ScienceGate 的相關結果
Background: Pyrimidine nucleotides are generated either by de novo synthesis or the salvage pathway in which pyrimidine nucleotides are obtained from the ... ... <看更多>
de novo pyrimidine synthesis 在 Pyrimidine Nucleotide Synthesis in the Normal and ... 的相關結果
ABSTRACT. Radioactive orotic acid incorporation into RNA (de novo pathway of pyrimidine nucleotide synthesis) was considerably lower for rat heart than for. ... <看更多>
de novo pyrimidine synthesis 在 Stimulation of the de novo pyrimidine synthesis - NYU's ... 的相關結果
Tag Stimulation of the de novo pyrimidine synthesis ... WE#8 SG Assignment, Stimulation de novo pyrimindine syn, Ben-Sahra Sci 2013. ... <看更多>
de novo pyrimidine synthesis 在 Stimulation of de novo biosynthesis of purine and pyrimidine ... 的相關結果
Third-degree burn injury covering 25% of the body surface was imposed on rats. The de novo biosynthesis of purine and pyrimidine nucleotides in the liver of ... ... <看更多>
de novo pyrimidine synthesis 在 'de novo' pyrimidine nucleobase biosynthetic process Gene ... 的相關結果
The chemical reactions and pathways resulting in the formation of pyrimidine nucleobases, 1,3-diazine, organic nitrogenous bases, beginning with the synthesis ... ... <看更多>
de novo pyrimidine synthesis 在 Brain pyrimidine nucleotide synthesis and Alzheimer disease 的相關結果
Many patients suffering late-onset Alzheimer disease show a deficit in respiratory complex IV activity. The de novo pyrimidine biosynthesis pathway connects ... ... <看更多>
de novo pyrimidine synthesis 在 Analysis of Pyrimidine Synthesis De Novo Intermediates in ... 的相關結果
Pathological conditions, such as a deficiency of UMP synthase result in altered excretion of intermediates of the pyrimidine de novo synthesis ... ... <看更多>
de novo pyrimidine synthesis 在 Pyrimidine Biosynthesis Analysis Service - Creative Proteomics 的相關結果
There are two routes to the synthesis of pyrimidines; nucleotides can be recycled by the salvage pathways or synthesized de novo from small metabolites. ... <看更多>
de novo pyrimidine synthesis 在 Analysis of the Zebrafish perplexed Mutation Reveals Tissue ... 的相關結果
CAD is required for de novo biosynthesis of pyrimidines that are required for DNA, RNA, and UDP-dependent protein glycosylation. Developmental ... ... <看更多>
de novo pyrimidine synthesis 在 Mitochondrial-Linked De Novo Pyrimidine ... - Research 的相關結果
Mitochondrial-Linked De Novo Pyrimidine Biosynthesis Dictates Human T-Cell Proliferation but Not Expression of Effector Molecules. ... <看更多>
de novo pyrimidine synthesis 在 Enzymatic De Novo Pyrimidine Nucleotide Synthesis - Figshare 的相關結果
Enzymatic De Novo Pyrimidine Nucleotide Synthesis. +Follow. Posted on 18.01.2011 - 16:00. The use of stable isotope labeling has revolutionized NMR studies ... ... <看更多>
de novo pyrimidine synthesis 在 Diversion of aspartate in ASS1-deficient tumours fosters de ... 的相關結果
Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis. Nature, Vol: 527, Page: 379-383. Department of Molecular Neurosceince ... ... <看更多>
de novo pyrimidine synthesis 在 Broad-spectrum antiviral that interferes with de novo ... 的相關結果
A3 appears to target dihydroorotate dehydrogenase (DHODH), an enzyme in the de novo pyrimidine biosynthesis pathway. It is found that viral replication of all ... ... <看更多>
de novo pyrimidine synthesis 在 Lecture 12 - Nucleotide Biosynthesis 的相關結果
The ring is synthesized first and then added to the ribose. The ammonia is produced from the hydrolysis of glutamine. 1. de Novo Synthesis of Pyrimidines ... ... <看更多>
de novo pyrimidine synthesis 在 Stimulation of de Novo Pyrimidine Synthesis by ... - NASA/ADS 的相關結果
Cellular growth signals stimulate anabolic processes. The mechanistic target of rapamycin complex 1 (mTORC1) is a protein kinase that senses growth signals ... ... <看更多>
de novo pyrimidine synthesis 在 Phenolic Amides Are Potent Inhibitors of De Novo Nucleotide ... 的相關結果
mitted step in de novo purine biosynthesis. Finally, external nucleoside ... purine and pyrimidine de novo biosynthesis and that these delete-. ... <看更多>
de novo pyrimidine synthesis 在 Modulating pyrimidine ribonucleotide levels for the treatment ... 的相關結果
The third enzyme of the de novo synthesis pathway is the bifunctional uridine monophosphate synthetase (UMPS) which catalyzes the formation of ... ... <看更多>
de novo pyrimidine synthesis 在 Synthesis of pyrimidine derivatives - Biochemistry Den 的相關結果
In the de-novo synthesis of pyrimidines, the ring is synthesized first, and then the pyrimidine ring is tacked onto the heterocyclic ring. Thus, the same amido- ... ... <看更多>
de novo pyrimidine synthesis 在 De novo pyrimidine synthesis is necessary for intestinal ... - Gale 的相關結果
Our data suggest that de novo pyrimidine synthesis is necessary for colonization of Salmonella Typhimurium in the chick, and that the salvage pathway is not ... ... <看更多>
de novo pyrimidine synthesis 在 Stimulation of de Novo Pyrimidine Synthesis by ... - CiteSeerX 的相關結果
stimulation of metabolic flux through the de novo pyrimidine synthesis pathway. mTORC1 signaling post-translationally regulated this ... ... <看更多>
de novo pyrimidine synthesis 在 Chapter-19 Nucleic Acid Metabolism - JaypeeDigital | eBook ... 的相關結果
Humans can synthesize purine and pyrimidine nucleotides de novo, i.e. ... ... <看更多>
de novo pyrimidine synthesis 在 Pyrimidine Biosynthesis: Notes | Draw it to Know it 的相關結果
Pyrmidine biosynthesis occurs via two key pathways: · De novo synthesis · Salvage pathway · Nucleoside vs Nucleotide · 5-phosphoribosyl-1-pyrophsophate (PRPP) ... ... <看更多>
de novo pyrimidine synthesis 在 32 Nitrogen: Nucleotide Metabolism - Basicmedical Key 的相關結果
5-phosphoribosyl-1-pyrophosphate (PRPP): activated form of ribose used in de novo synthesis of purine and pyrimidine nucleotides. ... <看更多>
de novo pyrimidine synthesis 在 What are the precursors for the de novo synthesis of pyrimidine? 的相關結果
The de novo biosynthesis of pyrimidine nucleotides provides essential precursors for multiple growth-related events in higher eukaryotes. ... <看更多>
de novo pyrimidine synthesis 在 To answer this question, YOu may reference the Metabolic ... 的相關結果
De novo nucleotide synthesis differs for purine and pyrimidine bases However; some molecules are important precursors and intermediates in both ... ... <看更多>
de novo pyrimidine synthesis 在 Pyrimidine Ribonucleotide Metabolism (Molecular Biology) 的相關結果
The biosynthesis of pyrimidine nucleotides is comparable to that of purine nucleotides in several important respects. Both rings are synthesized by de novo ... ... <看更多>
de novo pyrimidine synthesis 在 de novo synthesis of pyrimidine - Me Gusta Aragón 的相關結果
Pyrimidine metabolism: de novo synthesis of UMP. 20.3.1.3. Pharmacologic inhibition of de novo pyrimidine synthesis sensitizes TNBC cells to ... ... <看更多>
de novo pyrimidine synthesis 在 De Novo嘧啶合成 的相關結果
错误代码:1020. ... <看更多>
de novo pyrimidine synthesis 在 Marks' Essential Medical Biochemistry - 第 516 頁 - Google 圖書結果 的相關結果
34 Purine and Pyrimidine Metabolism CHAPTER OUTLINE 1 . PURINES AND PYRIMIDINES III . SYNTHESIS OF THE PYRIMIDINE NUCLEOTIDES A. De novo synthesis B. ... <看更多>
de novo pyrimidine synthesis 在 Annual Report - 第 1 卷 - 第 372 頁 - Google 圖書結果 的相關結果
Effect of PALA on De Novo Pyrimidine Biosynthesis in Cultured L1210 and Lewis Lung Carcinoma Cells Since PALA is curative against Lewis lung carcinoma in ... ... <看更多>
de novo pyrimidine synthesis 在 Annual Report - National Cancer Institute, Division of ... 的相關結果
Effect of PALA on De Novo Pyrimidine Biosynthesis in Cultured L1210 and Lewis Lung Carcinoma Cells Since PALA is curative against Lewis lung carcinoma in ... ... <看更多>
de novo pyrimidine synthesis 在 Plant Nucleotide Metabolism: Biosynthesis, Degradation, and ... 的相關結果
Biosynthesis, Degradation, and Alkaloid Formation Hiroshi Ashihara, Alan Crozier, ... UMP produced by the pyrimidine nucleotide biosynthesis de novo is ... ... <看更多>
de novo pyrimidine synthesis 在 Inborn Metabolic Diseases: Diagnosis and Treatment 的相關結果
35.2· Inborn Errors of Pyrimidine Metabolism 35.1.20 ... mutations in CAD gene resulted in impaired de novo pyrimidine synthesis and decreased glycosylation ... ... <看更多>
de novo pyrimidine synthesis 在 Metabolism in Cancer - 第 56 頁 - Google 圖書結果 的相關結果
4.2 Nucleotide Biosynthesis By stimulating the production of R5P through the PPP, the PI3K-Akt-mTOR network provides the building block for de novo ... ... <看更多>
de novo pyrimidine synthesis 在 USMLE Step 1 Lecture Notes 2020: Biochemistry and Medical ... 的相關結果
Digestion of endogenous nucleic acids (cell death, RNA turnover) In many cells, the capacity for de novo synthesis to supply purines and pyrimidines is ... ... <看更多>
de novo pyrimidine synthesis 在 Comprehensive Medicinal Chemistry III - 第 546 頁 - Google 圖書結果 的相關結果
... pyrimidines via the de novo route and thus they are highly vulnerable to inhibition of this pathway.27 In Plasmodium, de novo pyrimidine biosynthesis is ... ... <看更多>
de novo pyrimidine synthesis 在 Cumulated Index Medicus 的相關結果
Kavai I , et du De novo pyrimidine nucleotide biosynthesis in J Med Chem 18 ( 3 ) : 272-5 , Mar 75 synchronized rat hepatoma ( HTC ) cells and mouse ... ... <看更多>
de novo pyrimidine synthesis 在 Nucleotide Analogs [PDF] - staging 的相關結果
Thymidylate synthase (TS) is a highly conserved enzyme involved in the de novo synthesis of 2'-deoxythymidine monophosphate (thymidylate,. dTMP) ... ... <看更多>
de novo pyrimidine synthesis 在 De novo pyrimidine synthesis - Microbe Notes 的相關結果
Biosynthesis of pyrimidine nucleotides can occur by a de novo pathway or by the reutilization of preformed pyrimidine bases or ribonucleosides ( ... ... <看更多>