關於 cancer survival rates ，我們在網路上蒐集到這些相關的討論、資訊與評價

Spent the last 1 hour watching this sharing about advanced stage lung cancer. Covering on...
1. The alternative treatments available between chemo, radiotherapy, targeted therapy and immunotherapy
2. The success rates and the longer live span after receiving targeted treatments/ immunotherapy
3. Fundings by NGO and pharma company
4. Improved quality of life for patients
5. Clinical trial availability, pros and cons
6. Side effects of targeted therapy/ immunotherapy

It’s good to learn more and be educated about cancer so we can help n share the right info instead of the usual hearsay and myth. Very insightful sharing. And I’m happy to hear successful survival story of lung cancer fighters who has surpassed 10 years of survival

Amazing medical advancement we have in today’s world! ❤️👏🏼

https://www.facebook.com/nationalcancersocietymalaysia/videos/379729606599355/

加護病房查房日誌20201020
今天我們來看看Pembrolizumab這個Anti-PD-1 Monoclonal Antibody，和第一線的化療藥品，用於for mismatch repair-deficient metastatic colorectal cancer病人的效果吧。
大約有3-6%的metastatic colorectal cancers (mCRCs)病人在DNA mismatch repair (dMMR)是缺乏的。這類的病人在初始系統性化療失敗後，對於immune checkpoint inhibitor immunotherapy可能有潛在的好處。
在KEYNOTE-177 trial中初步結果建議使用Pembrolizumab作為第一線的治療，比起原先第一線的化療藥品有更好的效果。對於 progression-free survival 有兩倍，甚至更高的durable objective response rates，也有較少的嚴重不良反應。
文獻來源: Andre T, Shiu K-K, Kim T-W, et al. Pembrolizumab versus chemotherapy for microsatellite instability-high/mismatch repair deficient metastatic colorectal cancer: The phase 3 KEYNOTE-177 study (abstract). J Clin Oncol 38: 2020 (suppl; abstr LBA4). Abstract available online at https://meetinglibrary.asco.org/record/186928/abstract (Accessed on June 10, 2020).

但是目前overall survival data還沒有被發表，基於目前的證據，uptodate的學者建議對於 nonoperable dMMR mCRC 的病人，第一線使用pembrolizumab單一治療比化學治療來的好。在今年六月美國Food and Drug Administration (FDA) 也核准了pembrolizumab用於第一線治療patients with unresectable or metastatic dMMR CRC.。
只是在台灣目前這樣的適應症尚未通過，目前在台灣可用於1.黑色素細胞瘤，2.非小細胞肺癌，3.典型何杰金氏淋巴瘤，4.頭頸部鱗狀細胞癌，5.泌尿道上皮癌，6. 胃癌。

[SELF-LOVE]
Mammogram before Instagram!

I learned that catchy phrase at the Marie Claire Malaysia x #SLKLgoesPink event last week. As women, we must know the fact that in every 15 seconds, 1 woman is diagnosed with breast cancer in this world. That number is alarming!
We can’t change that fact for now but bear in mind that survival rates r more than 95% with early detection.
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So love thyself by:
1. Checking ur breast every month after your period. If u find any unusual bump/s, go to the gynecologist for a mammogram for further details.
2. Go for a medical checkup yearly with breast check included. It is never too early to start this practice.

Pink ribbons r not just for decorative purpose. It’s a reminder that action must be taken!
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#pinkoctober #breastcancerawareness