關於 axin1 ，我們在網路上蒐集到這些相關的討論、資訊與評價

#11. The Axin1 scaffold protein promotes formation ... - EMBO Press

Axin1 is a multi-domain scaffold protein that coordinates several different protein complexes that are involved in regulating Wnt, TGFβ, SAPK/JNK, ...

#12. AXIN1 protein expression summary - The Human Protein Atlas

Describes the main and potential additional location(s) of the encoded protein according to ICC-IF resukt in the Cell Atlas, as well as potential data regarding ...

#13. Axin 1 (AXIN1) (NM_181050) Human Recombinant Protein

Recombinant protein of human axin 1 (AXIN1), transcript variant 2.

#14. Axin1 MGI Mouse Gene Detail - MGI:1096327 - axin 1

View mouse Axin1 Chr17:26357662-26414785 with: phenotypes, sequences, polymorphisms, proteins, references, function, expression.

#15. A novel protein AXIN1-295aa encoded by circAXIN1 activates ...

AXIN1 is presumed to be a tumor suppressor [39, 40] in many types of cancers, especially colorectal cancer (CRC) [41, 42]. Both somatic and ...

#16. KEGG T01001: AXIN1

Symbol. AXIN1, AXIN, PPP1R49. Name. (RefSeq) axin 1. KO. K02157, axin 1. Organism. hsa Homo sapiens (human). Pathway. hsa04310, Wnt signaling pathway ...

#17. 則包含該關鍵詞出現在任一欄位(含基本資料及摘要)的所有計畫

APC，AXIN1，及E-Cadherin 抑瘤基因在功能上與β-catenin 有密 ... 關鍵字：Axin1； Axin2； Wnt/β-catenin； 神經退化； 創傷性腦損傷 。相對的，Axin1 及Axin2被認為 ...

#18. Differential effects of inactivated Axin1 and activated β-catenin ...

Axin1 is a multidomain scaffold protein implicated in various signaling pathways, including the Wnt, JNK, transforming growth factor (TGF)β and ...

#19. AXIN1 Mutation - My Cancer Genome

AXIN1 Mutation is present in 1.15% of AACR GENIE cases, with colon adenocarcinoma, lung adenocarcinoma, cutaneous melanoma, endometrial endometrioid ...

#20. Flag-Axin1 (Plasmid #109370) - Addgene

Plasmid Flag-Axin1 from Dr. Mariann Bienz's lab contains the insert Axin1 and is published in Proc Natl Acad Sci U S A. 2011 Feb 1;108(5):1937-42. doi: ...

#21. axin 1 (human) - PhosphoSite

axin 1 Component of the beta-catenin destruction complex required for ... Also component of the AXIN1-HIPK2-TP53 complex which controls cell growth, ...

#22. Axin-1 (AXIN1) Recombinant Protein - MyBioSource

Buy AXIN1 recombinant protein, Axin-1 (AXIN1) Recombinant Protein-NP_003493.1 (MBS1264908) product datasheet at MyBioSource, Recombinant Proteins.

#23. DVL recruits GSK3beta:AXIN1 to the receptor complex

The DIX domains of DVL and AXIN interact and this interaction brings GSK3beta:AXIN1 to the receptor complex (Schwarz-Romond et al, 2007).

#24. Axin1 (axin 1) - Rat Genome Database

ENCODES a protein that exhibits armadillo repeat domain binding; beta-catenin binding; identical protein binding; INVOLVED IN negative regulation of ...

#25. Axin-1 Antibody - BSA Free (NBP1-76483) - Novus Biologicals

Cited in 1 publications. View Rabbit Polyclonal anti-Axin-1 Antibody - BSA Free (NBP1-76483). Validated Applications: WB, ELISA, ICC/IF.

#26. Mouse AXIN1 / Axin-1 Protein Recombinant 6His, N-terminus

AXIN1 / Axin-1 Protein LS-G14839 is a Recombinant Mouse AXIN1 / Axin-1 produced in E. coli aa 654-863 with 6His, N-terminus tag(s).

#27. (PDF) . AXIN1 (axin 1). - ResearchGate

PDF | URL: http://AtlasGeneticsOncology.org/Genes/AXIN1ID379ch16p13.html | Find, read and cite all the research you need on ResearchGate.

#28. AXIN1 protein (human) - STRING interaction network

AXIN1, Axin-1; Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and ...

#29. AXIN1/CCP16 FISH Probe Kit - CytoTest

The AXIN1/CCP16 FISH Probe Kit is designed to detect the human AXIN1 gene located on chromosome band 16p13.3, along with the number of chromosome 16 copies ...

#30. AXIN1 antibody (16541-1-AP) - Proteintech

Cited in 8 publications. AXIN1 antibody for IHC, WB,ELISA and reacts with human.

#31. Axin-1 | DrugBank Online

Name: Axin-1 · Synonyms. AXIN · Gene Name: AXIN1 · Organism: Humans · Amino acid sequence · Number of residues · Molecular Weight · Theoretical pI ...

#32. Abbreviation / Long Form : AXIN1 / axis inhibition protein 1 - Allie

A Search Service for Abbreviation / Long Form. □ Abbreviation / Long Form : AXIN1 / axis inhibition protein 1. [Related PubMed/MEDLINE]

#33. AXIN1 Expression and Localization in Meningiomas and ...

Background/Aim. Tumor suppressor gene AXIN1 is an inhibitor of Wnt signaling pathway. It down-regulates the pathway's main signaling effector molecule, beta- ...

#34. Detection of point mutations of the Axin1 gene in colorectal ...

To gain further insights into the structure and function of Axin in controlling cell growth, we analyzed 54 colorectal cancer tissues for mutations in AXIN1 ...

#35. Axin1 antibody Western A2231 - Sigma-Aldrich

Anti-Axin1 (C-terminal region) antibody produced in rabbit ~2.5&#. All Photos(1). Synonym(s): Anti-Axis Inhibitor 1, Anti-Axis inhibition protein 1, ...

#36. AXIN1 Single Gene - Fulgent Genetics

Sequence variants and/or copy number variants (deletions/duplications) within the AXIN1 gene will be detected with >99% sensitivity.

#37. AXIN1 Hallmarks of Cancer - COSMIC

AXIN1 Hallmarks of Cancer. Explore the role of AXIN1 in cancer within the context of the hallmarks behaviours and functional descriptions. AXIN1 axin 1.

#38. Anti-Axin 1 antibody (ab133221) - Abcam

Rabbit polyclonal Axin 1 antibody. Validated in IHC and tested in Human. Immunogen corresponding to synthetic peptide.

#39. Human Axin 1 (AXIN1) Protein (His tag), Recombinant

Recombinant Axin 1 (AXIN1) Protein (His tag). Species: Human. Source: Insect Cells. Order product ABIN3089641.

#40. Anti-Axin-1 Antibody | 06-1049 - Merck Millipore

Axin-1 mutation has been linked to oral squamous cell carcinoma. Axin-1 binds to GSK3alpha and activates the Wnt signaling pathway which is shown to be ...

#41. AXIN1 (axin 1) | Gene Report - BioGPS

This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain.

#42. Differential Roles of AXIN1 and AXIN2 in Tankyrase Inhibitor ...

Since the role of AXIN1 versus AXIN2 as scaffolding proteins in the Wnt signaling pathway still remains incompletely understood, ...

#43. AXIN1 (LA16c-314G4.3) Result Summary - BioGRID

Interactor Organism /; Chemical Type Evidence GSK3B H. sapiens 931View CTNNB1 H. sapiens 323View APC H. sapiens 111View

#44. AXIN1 Antibody | F45423 NSJ Bioreagents

AXIN1 is a component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, ...

#45. AXIN1 | Cancer Genetics Web

Gene: AXIN1; axin 1. Aliases: AXIN, PPP1R49. Location: 16p13.3. Summary: This gene encodes a cytoplasmic protein which contains a regulation of G-protein ...

#46. Conditional Disruption of Axin1 Leads to Development of Liver ...

BACKGROUND & AIMS: Mutations in components of the Wnt signaling pathway, including ß-catenin and. AXIN1, are found in more than 50% of human hepato-.

#47. Effect of CRISPR Knockout of AXIN1 or ARID1A on ... - Frontiers

Simultaneous knockout of AXIN1 and ARID1A increased the migration, but did not alter the proliferation of porcine HCC cells. The effect of gene ...

#48. WNT/β-catenin pathway activation via Wnt1 overexpression ...

WNT/β-catenin pathway activation via Wnt1 overexpression and Axin1 downregulation correlates with cadherin-catenin complex disruption and increased lymph ...

#49. Phase separation of Axin organizes the β-catenin destruction ...

Both Axin1 and Axin2 proteins harbor multiple protein-binding domains, including the N-terminal Regulators of G protein Signaling (RGS) domain ...

#50. Axin-1 Products - R&D Systems

Axin-1 : Products. Axin-1 is a negative regulator of the Wnt signaling pathway, which is involved in regulation of embryonic axis formation in vertebrates.

#51. Analysis of binding interfaces of the human scaffold protein ...

AXIN1 contains several binding epitopes for CK1ϵ, c-Myc, p53, and Pin1. All Axin proteins have a conserved structure with two well-defined ...

#52. Mutational spectrum of beta-catenin, AXIN1, and AXIN2 in ...

To explore the contribution of additional Wnt pathway molecules to hepatocarcinogenesis, we examined beta-catenin, AXIN1 and AXIN2 mutations in 73 HCCs and ...

#53. LGALS3 and AXIN1 gene variants playing role in the Wnt

LGALS3 and AXIN1 gene variants playing role in the Wnt/ β-catenin signaling pathway are associated with mucinous component and tumor size in colorectal cancer ...

#54. Axin1 - Xenopus laevis and Xenopus tropicalis - Xenbase

axin1. Gene Name : axin 1. Synonyms: xAxin , axin , fused ( Add synonyms , Nomenclature history ). Gene Function: negative regulator of the wnt signaling ...

#55. Axin1 (C95H11) Rabbit mAb from Cell Signaling Technology

Compare Axin1 (C95H11) Rabbit mAb 2074S from Cell Signaling Technology on Biocompare.com.

#56. AXIN1 - actrec.gov.in

Wild-type axin 1 can induce apoptosis in hepatocellular and colorectal cancer cells. Enhances TGF-beta signaling by recruiting the RNF111 E3 ubiquitin ...

#57. Deletions of AXIN1, a Component of the WNT/wingless ...

The presence of AXIN1 mutations suggests that different alterations in the WNT pathway may lead to an overactivation of WNT signaling in MBs. In MBs of the ...

#58. Axin-1 (human), (recombinant) - ENZ-PRT130

Axin-1 (human), (recombinant) - ENZ-PRT130.

#59. AXIN1 - Cusabio - 华美生物

Axin-1 is a protein in humans that is encoded by AXIN1 gene. Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through ...

#60. Human Gene AXIN1 (ENST00000262320.8) from GENCODE ...

Description: Homo sapiens axin 1 (AXIN1), transcript variant 1, mRNA. (from RefSeq NM_003502) RefSeq Summary (NM_003502): This gene encodes ...

#61. AXIN1 mutations in hepatocellular carcinomas, and growth ...

Adenovirus mediated gene transfer of wild-type AXIN1 induced apoptosis in hepatocellular and colorectal cancer cells that had accumulated ...

#62. AXIN1 in Plasma or Serum Is a Potential New Biomarker for ...

Although endometriosis is considered an inflammatory disease, no reliable diagnostic biomarkers exist for use in clinical practice.

#63. Anti-Axin-1 Antibody | 06-1049 - EMD Millipore

Axin-1 mutation has been linked to oral squamous cell carcinoma. Axin-1 binds to GSK3alpha and activates the Wnt signaling pathway which is shown to be ...

#64. AXIN1 cDNA Clones Research Reagents - Sino Biological

We have professional and advanced research and production capacity for AXIN1 reagents production, including cDNA Clones,etc. All AXIN1 products are produced ...

#65. AXIN1 | gnomAD v2.1.1

Constraint metrics based on Ensembl canonical transcript (ENST00000262320.3). Viewing full gene. Zoom in. exome; genome.

#66. AXIN1 Protein - SignalChem

AXIN1 Protein. Full-length recombinant human protein expressed in Sf9 cells. Catalog # A71-30G. Lot # E3330-6. Product Description.

#67. Genetic association of polymorphisms in AXIN1 gene with ...

Aim: The purpose of the present study is to investigate the association between the polymorphisms in AXIN1 with susceptibility to clear cell ...

#68. JMD : Journal of Movement Disorders

AXIN1 promotes the GSK-3β phosphorylation of β-catenin and subsequent degradation of β-catenin in the canonical Wnt pathway, resulting in reduced Wnt expression ...

#69. Wnt/β-Catenin Signaling and AXIN1 Regulate Apoptosis ...

Furthermore, knockdown of AXIN1 by small interfering RNA (siRNA) sensitized melanoma cell lines otherwise resistant to apoptosis after BRAF V600E inhibition.

#70. A mutation in the Gsk3–binding domain of zebrafish ...

Our data reveal a crucial role for Axin1-dependent inhibition of the Wnt pathway in the early regional subdivision of the anterior neural plate into ...

#71. AXIN1 antibody | 5 products in Validated Antibody Database

Axin-1 Antibody R&D Systems catalog: AF3287. domestic goat polyclonal reactivity: human, mouse, rat application: western blot citations: 5.

#72. Wnt/Axin1/β-Catenin Signaling Regulates Asymmetric Nodal ...

Downstream of Nodal pathway activity in the epithalamus, Axin1 is required both for development and concordance of parapineal and habenular asymmetries.

#73. Axin1 的特异性缺失导致β-连环蛋白/BMP 信号传导的激活

Axin1 and Axin2 are key regulators of canonical Wnt signaling pathway. The roles of Axin1 and Axin2 in skeletal development and in disease ...

#74. AXIN1 (axin 1)

Axin 1 consists of 11 exons (isoform a). Full gene transcript product length is 3675 bp. Isoform b lacks an in-frame exon in the 3 coding region ...

#75. anti-GSK3B, AXIN1 Protein Protein Interaction Antibody Pair ...

Includes: GSK3B rabbit purified polyclonal antibody (20μg); AXIN1 mouse monoclonal antibody (40μg); Reagents are sufficient for at least 30-50 assays using ...

#76. AXIN1 - PharmGKB

PharmGKB ID. PA25195 ; HGNC Approved Name. axin 1 ; Alternate Names. protein phosphatase 1, regulatory subunit 49 ; Alternate Symbols. PPP1R49.

#77. axin1 | Danio rerio gene - Alliance of Genome Resources

Human ortholog(s) of this gene implicated in hepatocellular carcinoma; lung cancer; and urinary bladder cancer. Orthologous to human AXIN1 (axin 1).

#78. AXIN1 DepMap Gene Summary

AXIN1. axin 1. Location: Also known as: PPP1R49. Ensembl: ENSG00000103126. NCBI Entrez Gene: 8312. Dependent Cell Lines. CRISPR (DepMap 22Q2 Public+Score, ...

#79. Human Axis Inhibition Protein 1 (AXIN1) ELISA Kit | Abbexa Ltd

Human Axis Inhibition Protein 1 (AXIN1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Axis Inhibition Protein 1 (AXIN1) ...

#80. Association between AXIN1 Gene Polymorphisms and ...

Background. Previous evidence has indicated that the reduction of axis inhibition protein 1 (AXIN1) expression is related with the poor ...

#81. A Pan-Cancer Analysis of AXIN1. - Research Square

We observed an increase phosphorylation level of S486/S493 in breast cancer and UCEC (Uterine Corpus. Endometrial Carcinoma). AXIN1 expression ...

#82. AXIN1 monoclonal antibody (M01), clone 2B11 - Abnova

Mouse monoclonal antibody raised against a partial recombinant AXIN1. AXIN1 (NP_003493, 643 a.a. ~ 740 a.a) partial recombinant protein with GST tag.

#83. The AXIN1 gene homepage - Global Variome shared LOVD

General information. Gene symbol, AXIN1. Gene name, axin 1. Chromosome, 16. Chromosomal band, p13.3. Imprinted, Unknown.

#84. Alterations of Axis Inhibition Protein 1 (AXIN1) in Hepatitis B V...

Overexpression of AXIN1 wild-type but not AXIN1 mutant inhibited the growth of HCC cell lines, accelerated their apoptosis, and negatively ...

#85. AXIN1 | JCGA

AXIN1 (AXIN)はWNTシグナルのメディエーターであるβ-カテニンを制御するβ-カテニン分解複合体の構成分子であり、WNTシグナルの抑制に働く。WNTリガンドの非結合時 ...

#86. WNT-3A Regulates an Axin1/NRF2 Complex That Regulates ...

Axin1 is an essential element of the WNT signalosome that scaffolds specific kinases and substrates together (36). To study the possible ...

#87. The links between axin and carcinogenesis

Axin1 (also simply called Axin), which encodes isoforms a and b, and Axin2 (also called Axil or Conductin) have 45% identity at the nucleotide level and the ...

#88. The Synthetic Small Molecule FL3 Combats Intestinal ...

Unlike Axin2, which is a transcriptional target of β-catenin-dependent Wnt signaling, Axin1 is ubiquitously expressed and is classically thought of as a tumor ...

#89. Cancer Signaling: From Molecular Biology to Targeted Therapy

Axin1 comprises 862 amino acids, Axin2 comprises 843 amino acids. Mutations in the AXIN1 gene are distributed over the entire sequence, whereas mutations in ...

#90. Anti-AXIN1 / Axin-1 Antibody (HRP) MX-C543639

Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating ...

#91. Colorectal Cancer: Surgery, Diagnostics and Treatment

Axin Axin1 (also simply called Axin), which encodes isoformaand b, and Axin2 (also called Axil or Conductin) have 45%identity at the nucleotide level and ...

#92. Principles of Cancer Genetics - 第 232 頁 - Google 圖書結果

Friz/Dish/LRP b-cat b-cat TCF4 E-cadherin WNTligand APC Altered cell-cell GSK3 β-catenin degradation AXIN1 MYC CCND1 adhesion complex R-spondin Cytoplasm ...

#93. Molecular Oncology - 第 248 頁 - Google 圖書結果

Armadillo repeats of -catenin are involved in interactions with a variety of proteins, such as APC,AXIN1, AXIN2, -catenin, BCL9, BRG1, CBP/p300, E-cadherin, ...

#94. Cumulative Haploinsufficiency and Triplosensitivity ... - CORE

AXIN1. GSK3B. LEF. RSPO2. MAP3K1. MAP2K4. BRAF. KRAS. NRAS. HRAS. MAPK1. MAP2K1. TGFBR2. TGFBR1. TGFB1. ACVR1B. Activin. SMAD4. SMAD2. TGF−β Signaling.

#95. Zahradní pohovka - Šenov u Nového Jičína, Nový Jičín - Sbazar

ratanová sestava Axin 1. Inzerát byl odebran z oblíbených. 5 200 KčTýniště nad Orlicí. nábytek, křeslo, pohovka, stul. Inzerát byl odebran z oblíbených.

#96. MacSween's Pathology of the Liver E-Book

AXIN1 mutations in hepatocellular carcinomas and growth suppression in cancer cells by virus-mediated transfer of AXIN1.

#97. Dr wang gastroenterologist. Hwang was recognized by Boston ...

... protein 1 (Axin1) Deletion-Induced Hepatocarcinogenesis Requires Intact ß-Catenin but Not Notch Cascade in Mice He emphasizes preventative treatment, ...